Mary L. Holtz, Ph.D.

Affiliations: 
2000 University of Kentucky, Lexington, KY 
Area:
Neuroscience Biology, Toxicology, Molecular Biology
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L Creed Pettigrew grad student 2000 University of Kentucky
 (Involvement of nitric oxide synthase enzymes in the development of neuronal degeneration following glutamate excitotoxicity.)
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Publications

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Pettigrew LC, Holtz ML, Kindy MS, et al. (2005) The TNFalpha-transgenic rat: A new model of cytokine-mediated ischemic brain injury Journal of Cerebral Blood Flow & Metabolism. 25: S106-S106
Pettigrew LC, Holtz ML, Minger SL, et al. (2003) Glutamate receptor antagonists modulate heat shock protein response in focal brain ischemia. Neurological Research. 25: 201-7
Holtz ML, Craddock SD, Pettigrew LC. (2001) Rapid expression of neuronal and inducible nitric oxide synthases during post-ischemic reperfusion in rat brain. Brain Research. 898: 49-60
Minger SL, Geddes JW, Holtz ML, et al. (1998) Glutamate receptor antagonists inhibit calpain-mediated cytoskeletal proteolysis in focal cerebral ischemia. Brain Research. 810: 181-99
Pettigrew LC, Holtz ML, Craddock SD, et al. (1996) Microtubular proteolysis in focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 16: 1189-202
Geddes JW, Pettigrew LC, Holtz ML, et al. (1996) Permanent focal and transient global cerebral ischemia increase glial and neuronal expression of heme oxygenase-1, but not heme oxygenase-2, protein in rat brain. Neuroscience Letters. 210: 205-8
Holtz ML, Kindy MS, Craddock S, et al. (1996) Induction of PGH synthase and c-fos mRNA during early reperfusion of ischemic rat brain. Brain Research. Molecular Brain Research. 35: 339-43
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