Feng-Shiun Shie, Ph.D.

Affiliations: 
2000 University of Washington, Seattle, Seattle, WA 
Area:
Neuroscience Biology, Nutrition, Pathology
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"Feng-Shiun Shie"
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Parents

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Renee C. LeBoeuf grad student 2000 University of Washington
 (Cholesterol and Alzheimer's disease.)
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Publications

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Tsay HJ, Gan YL, Su YH, et al. (2024) Reducing brain Aβ burden ameliorates high-fat diet-induced fatty liver disease in APP/PS1 mice. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 173: 116404
Huang YC, Hsu SM, Shie FS, et al. (2022) Reduced mitochondria membrane potential and lysosomal acidification are associated with decreased oligomeric Aβ degradation induced by hyperglycemia: A study of mixed glia cultures. Plos One. 17: e0260966
Su IJ, Hsu CY, Shen S, et al. (2022) The Beneficial Effects of Combining Anti-Aβ Antibody NP106 and Curcumin Analog TML-6 on the Treatment of Alzheimer's Disease in APP/PS1 Mice. International Journal of Molecular Sciences. 23
Lai RH, Hsu YY, Shie FS, et al. (2021) Non-genomic rewiring of vitamin D receptor to p53 as a key to Alzheimer's disease. Aging Cell. e13509
Hsu JT, Tien CF, Yu GY, et al. (2021) The Effects of Aβ Binding to the SARS-CoV-2 Spike Protein S1 Subunit and Angiotensin-Converting Enzyme 2. International Journal of Molecular Sciences. 22
Yeh SH, Shie FS, Liu HK, et al. (2019) A high-sucrose diet aggravates Alzheimer's disease pathology, attenuates hypothalamic leptin signaling, and impairs food-anticipatory activity in APPswe/PS1dE9 mice. Neurobiology of Aging
Lee YH, Hsu HC, Kao PC, et al. (2018) Augmented Insulin and Leptin Resistance of High Fat Diet-Fed APPswe/PS1dE9 Transgenic Mice Exacerbate Obesity and Glycemic Dysregulation. International Journal of Molecular Sciences. 19
Yeh CW, Yeh SH, Shie FS, et al. (2015) Impaired cognition and cerebral glucose regulation are associated with astrocyte activation in the parenchyma of metabolically stressed APPswe/PS1dE9 mice. Neurobiology of Aging
Shie FS, Shiao YJ, Yeh CW, et al. (2015) Obesity and Hepatic Steatosis Are Associated with Elevated Serum Amyloid Beta in Metabolically Stressed APPswe/PS1dE9 Mice. Plos One. 10: e0134531
Yang CN, Shiao YJ, Shie FS, et al. (2011) Mechanism mediating oligomeric Aβ clearance by naïve primary microglia. Neurobiology of Disease. 42: 221-30
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