Kevin J. Paavola

Orphan GPCRs

Randy A. Hall	grad student	2005-2012	Emory
(Signaling and Regulation of the Polymicrogyria-associated receptor GPR56: A Model Biochemical Study of the Adhesion G Protein-coupled Receptor Family.)

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Galon-Tilleman H, Yang H, Bednarek MA, et al. (2016) Apelin-36 Modulates Blood Glucose and Body Weight Independently of Canonical APJ Signaling. The Journal of Biological Chemistry
Ravenscroft G, Nolent F, Rajagopalan S, et al. (2015) Mutations of GPR126 are responsible for severe arthrogryposis multiplex congenita. American Journal of Human Genetics. 96: 955-61
Paavola KJ, Sidik H, Zuchero JB, et al. (2014) Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126. Science Signaling. 7: ra76
Stephenson JR, Paavola KJ, Schaefer SA, et al. (2013) Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density. The Journal of Biological Chemistry. 288: 22248-56
Paavola KJ, Hall RA. (2012) Adhesion G protein-coupled receptors: signaling, pharmacology, and mechanisms of activation. Molecular Pharmacology. 82: 777-83
Paavola KJ, Stephenson JR, Ritter SL, et al. (2011) The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity. The Journal of Biological Chemistry. 286: 28914-21
Ritter SL, Asay MJ, Paquet M, et al. (2011) GLAST stability and activity are enhanced by interaction with the PDZ scaffold NHERF-2. Neuroscience Letters. 487: 3-7