Kelly Seaton, Ph.D.

Affiliations: 
2009 Pennsylvania State University, State College, PA, United States 
Area:
Pharmacology, Virology Biology
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Jong K. Yun grad student 2009 Penn State
 (The human N-myristoyltransferases as potential pharmacotherapeutic targets in HIV-1 replication.)
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Publications

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Walsh SR, Gay CL, Karuna ST, et al. (2024) A Randomised Clinical Trial of the Safety and Pharmacokinetics of VRC07-523LS Administered via Different Routes and Doses (HVTN 127/HPTN 087). Medrxiv : the Preprint Server For Health Sciences
Reeves DB, Mayer BT, deCamp AC, et al. (2023) High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials. Nature Communications. 14: 8299
Sobieszczyk ME, Mannheimer S, Paez CA, et al. (2023) Safety, tolerability, pharmacokinetics, and immunological activity of dual-combinations and triple-combinations of anti-HIV monoclonal antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS administered intravenously to HIV-uninfected adults: a phase 1 randomised trial. The Lancet. Hiv. 10: e653-e662
Chirenje ZM, Laher F, Dintwe O, et al. (2023) Protein dose-sparing effect of AS01B adjuvant in a randomized preventive HIV vaccine trial of ALVAC-HIV (vCP2438) and adjuvanted bivalent subtype C gp120. The Journal of Infectious Diseases
Tieu HV, Karuna S, Huang Y, et al. (2023) Safety and immunogenicity of a recombinant oligomeric gp145 subtype C Env protein (gp145 C.6980) HIV vaccine candidate in healthy, HIV-1-uninfected adult participants in the US. Vaccine
Seaton KE, Huang Y, Karuna S, et al. (2023) Pharmacokinetic serum concentrations of VRC01 correlate with prevention of HIV-1 acquisition. Ebiomedicine. 93: 104590
Huang Y, Zhang Y, Seaton KE, et al. (2022) Baseline host determinants of robust human HIV-1 vaccine-induced immune responses: A meta-analysis of 26 vaccine regimens. Ebiomedicine. 84: 104271
Gilbert PB, Huang Y, deCamp AC, et al. (2022) Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition. Nature Medicine
Moodie Z, Dintwe O, Sawant S, et al. (2022) Analysis of the HVTN 702 Phase 2b-3 HIV-1 vaccine trial in South Africa assessing RV144 antibody and T-cell correlates of HIV-1 acquisition risk. The Journal of Infectious Diseases
Tomalka JA, Pelletier AN, Fourati S, et al. (2021) The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination. Nature Immunology
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