Irene Tiemann-Boege, Ph.D.

2003 University of Southern California, Los Angeles, CA, United States 
Genetics, Molecular Biology
"Irene Tiemann-Boege"
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Norman Arnheim grad student 2003 USC
 (Quantification of mutations causing achondroplasia: A study of the paternal age effect.)
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Arbeithuber B, Thuenauer R, Gravogl Y, et al. (2015) Aquaporin 5 expression in mouse mammary gland cells is not driven by promoter methylation. Biomed Research International. 2015: 460598
Arbeithuber B, Betancourt AJ, Ebner T, et al. (2015) Crossovers are associated with mutation and biased gene conversion at recombination hotspots. Proceedings of the National Academy of Sciences of the United States of America. 112: 2109-14
Shinde DN, Elmer DP, Calabrese P, et al. (2013) New evidence for positive selection helps explain the paternal age effect observed in achondroplasia. Human Molecular Genetics. 22: 4117-26
Boulanger J, Muresan L, Tiemann-Boege I. (2012) Massively parallel haplotyping on microscopic beads for the high-throughput phase analysis of single molecules. Plos One. 7: e36064
Meyer WK, Arbeithuber B, Ober C, et al. (2012) Evaluating the evidence for transmission distortion in human pedigrees. Genetics. 191: 215-32
Hilber W, Tiemann-Boege I, Diskus C, et al. (2010) Parallel dna amplification using localized microwave heating in standard-microtubes 14th International Conference On Miniaturized Systems For Chemistry and Life Sciences 2010, Microtas 2010. 1: 88-90
Tiemann-Boege I, Curtis C, Shinde DN, et al. (2009) Product length, dye choice, and detection chemistry in the bead-emulsion amplification of millions of single DNA molecules in parallel. Analytical Chemistry. 81: 5770-6
Arnheim N, Calabrese P, Tiemann-Boege I. (2007) Mammalian meiotic recombination hot spots. Annual Review of Genetics. 41: 369-99
Qin J, Calabrese P, Tiemann-Boege I, et al. (2007) The molecular anatomy of spontaneous germline mutations in human testes. Plos Biology. 5: e224
Wyrobek AJ, Eskenazi B, Young S, et al. (2006) Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm. Proceedings of the National Academy of Sciences of the United States of America. 103: 9601-6
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