George Paul Hess, A.B., Ph.D.

Affiliations: 
Molecular Biology & Genetics Cornell University, Ithaca, NY, United States 
Area:
caged neurotransmitters, photolysis, kinetics, nicotinic acetylcholine, GABA(A), NMDA, glutamate, glycine, receptors, inhibitors, epilepsy
Website:
http://www.news.cornell.edu/stories/2015/09/george-hess-biochemist-dies-92
Google:
"George P Hess"
Bio:

(1926 - 2015)
http://www.nasonline.org/member-directory/deceased-members/15525.html
http://mbg.cornell.edu/cals/mbg/faculty-staff/faculty/hess.cfm
http://www.news.cornell.edu/stories/April09/ArtsSciFellowHess.html

Mean distance: 17.74 (cluster 32)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Choh Hao Li grad student 1951 UC Berkeley (Chemistry Tree)
John Clark Sheehan post-doc MIT

Children

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Tracy Milburn research assistant Cornell
Peter S. Kim research assistant 1977-1979 Cornell (Chemistry Tree)
One Pagan grad student Cornell
Satoru Shiono grad student Cornell
Raymond Wieboldt grad student Cornell
Pierre Leprince grad student 1977-1980 Cornell
Jeffrey Karpen grad student 1985 Cornell
Anne Delcour grad student 1986 Cornell
Jayant Udgaonkar grad student 1981-1986 Cornell (Chemistry Tree)
Katherine Walstrom grad student 1993 Cornell
Ryan W. Lewis grad student 2011 Cornell
John Andrews post-doc Cornell
Hitoshi Aoshima post-doc Cornell
Anamitro Banerjee post-doc Cornell
Andrew Billington post-doc Cornell
Hans-Georg Breitinger post-doc Cornell
Derek Cash post-doc Cornell
Yongli Chen post-doc Cornell
Juian-juian Fu post-doc Cornell
Norihisa Fujita post-doc Cornell
Armanda Gameiro post-doc Cornell
Natarajan Geetha post-doc Cornell
Christof Grewer post-doc Cornell
Vasanthi Jayaraman post-doc Cornell
Heyi Li post-doc Cornell
Norio Matsubara post-doc Cornell
Li Niu post-doc Cornell
Elena Pasquale post-doc Cornell
Latha Ramakrishnan post-doc Cornell
Doraiswamy Ramesh post-doc Cornell
Helga Rübsamen-Schaeff post-doc Cornell
Klaus Schaper post-doc Cornell
Vishakha Shembekar post-doc Cornell
Kannan Sivaprakasam post-doc Cornell
Sanjay Srivastava post-doc Cornell
Melody Sweet post-doc Cornell
Henning Ulrich post-doc Cornell
Karl G. Brandt post-doc 1966 Cornell (Chemistry Tree)
Jeffery William Walker post-doc 1985 Cornell (Physiology Academic Tree)

Collaborators

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David M. Blow collaborator MRC-LMB (Chemistry Tree)
Barry K. Carpenter collaborator Cornell (Chemistry Tree)
Winfried Denk collaborator Cornell
Vincent du Vigneaud collaborator Cornell (Chemistry Tree)
Thomas Fox collaborator Cornell (Chemistry Tree)
Bruce Ganem collaborator Cornell
Murray Goodman collaborator MIT (Chemistry Tree)
Peter Lauger collaborator University of Konstanz
Aaron Lewis collaborator Cornell
John T. Lis collaborator Cornell (FlyTree)
Douglas Moore collaborator Cornell
Nathan Nelson collaborator Cornell
Robert Oswald collaborator Cornell (Chemistry Tree)
Watt W. Webb collaborator Cornell (Chemistry Tree)
BETA: Related publications

Publications

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Hess GP, Lewis RW, Chen Y. (2014) Caged neurotransmitters and other caged compounds: design and application. Cold Spring Harbor Protocols. 2014: pdb.top084152
Hess GP, Lewis RW, Chen Y. (2014) Cell-flow technique. Cold Spring Harbor Protocols. 2014: pdb.prot084160
Lewis RW, Hess GP, Ganem B. (2011) Use of multicomponent reactions in developing small-molecule tools to study GABAA receptor mechanism and function. Future Medicinal Chemistry. 3: 243-50
Ramakrishnan L, Hess GP. (2010) Mechanism of potentiation of a dysfunctional epilepsy-linked mutated GABA(A) receptor by a neurosteroid (3alpha, 21-dihydroxy-5alpha-pregnan-20-one): transient kinetic investigations. Biochemistry. 49: 7892-901
Lewis RW, Mabry J, Polisar JG, et al. (2010) Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant. Biochemistry. 49: 4841-51
Sivaprakasam K, Pagán OR, Hess GP. (2010) Minimal RNA aptamer sequences that can inhibit or alleviate noncompetitive inhibition of the muscle-type nicotinic acetylcholine receptor. The Journal of Membrane Biology. 233: 1-12
Fan L, Lewis RW, Hess GP, et al. (2009) A new synthesis of caged GABA compounds for studying GABAA receptors. Bioorganic & Medicinal Chemistry Letters. 19: 3932-3
Shembekar VR, Chen Y, Carpenter BK, et al. (2007) Coumarin-caged glycine that can be photolyzed within 3 microseconds by visible light. Biochemistry. 46: 5479-84
Krivoshein AV, Hess GP. (2006) On the mechanism of alleviation by phenobarbital of the malfunction of an epilepsy-linked GABA(A) receptor. Biochemistry. 45: 11632-41
Ramakrishnan L, Hess GP. (2005) Picrotoxin inhibition mechanism of a gamma-aminobutyric acid A receptor investigated by a laser-pulse photolysis technique. Biochemistry. 44: 8523-32
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