George Paul Hess, A.B., Ph.D.
Affiliations: | Molecular Biology & Genetics | Cornell University, Ithaca, NY, United States |
Area:
caged neurotransmitters, photolysis, kinetics, nicotinic acetylcholine, GABA(A), NMDA, glutamate, glycine, receptors, inhibitors, epilepsyWebsite:
http://www.news.cornell.edu/stories/2015/09/george-hess-biochemist-dies-92Google:
"George P Hess"Bio:
(1926 - 2015)
http://www.nasonline.org/member-directory/deceased-members/15525.html
http://mbg.cornell.edu/cals/mbg/faculty-staff/faculty/hess.cfm
http://www.news.cornell.edu/stories/April09/ArtsSciFellowHess.html
Mean distance: 17.74 (cluster 32) | S | N | B | C | P |
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Choh Hao Li | grad student | 1951 | UC Berkeley (Chemistry Tree) |
| John Clark Sheehan | post-doc | MIT |
Children
Sign in to add traineeCollaborators
Sign in to add collaborator| David M. Blow | collaborator | MRC-LMB (Chemistry Tree) | |
| Barry K. Carpenter | collaborator | Cornell (Chemistry Tree) | |
| Winfried Denk | collaborator | Cornell | |
| Vincent du Vigneaud | collaborator | Cornell (Chemistry Tree) | |
| Thomas Fox | collaborator | Cornell (Chemistry Tree) | |
| Bruce Ganem | collaborator | Cornell | |
| Murray Goodman | collaborator | MIT (Chemistry Tree) | |
| Peter Lauger | collaborator | University of Konstanz | |
| Aaron Lewis | collaborator | Cornell | |
| John T. Lis | collaborator | Cornell (FlyTree) | |
| Douglas Moore | collaborator | Cornell | |
| Nathan Nelson | collaborator | Cornell | |
| Robert Oswald | collaborator | Cornell (Chemistry Tree) | |
| Watt W. Webb | collaborator | Cornell (Chemistry Tree) |
BETA: Related publications
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Publications
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| Hess GP, Lewis RW, Chen Y. (2014) Caged neurotransmitters and other caged compounds: design and application. Cold Spring Harbor Protocols. 2014: pdb.top084152 |
| Hess GP, Lewis RW, Chen Y. (2014) Cell-flow technique. Cold Spring Harbor Protocols. 2014: pdb.prot084160 |
| Lewis RW, Hess GP, Ganem B. (2011) Use of multicomponent reactions in developing small-molecule tools to study GABAA receptor mechanism and function. Future Medicinal Chemistry. 3: 243-50 |
| Ramakrishnan L, Hess GP. (2010) Mechanism of potentiation of a dysfunctional epilepsy-linked mutated GABA(A) receptor by a neurosteroid (3alpha, 21-dihydroxy-5alpha-pregnan-20-one): transient kinetic investigations. Biochemistry. 49: 7892-901 |
| Lewis RW, Mabry J, Polisar JG, et al. (2010) Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant. Biochemistry. 49: 4841-51 |
| Sivaprakasam K, Pagán OR, Hess GP. (2010) Minimal RNA aptamer sequences that can inhibit or alleviate noncompetitive inhibition of the muscle-type nicotinic acetylcholine receptor. The Journal of Membrane Biology. 233: 1-12 |
| Fan L, Lewis RW, Hess GP, et al. (2009) A new synthesis of caged GABA compounds for studying GABAA receptors. Bioorganic & Medicinal Chemistry Letters. 19: 3932-3 |
| Shembekar VR, Chen Y, Carpenter BK, et al. (2007) Coumarin-caged glycine that can be photolyzed within 3 microseconds by visible light. Biochemistry. 46: 5479-84 |
| Krivoshein AV, Hess GP. (2006) On the mechanism of alleviation by phenobarbital of the malfunction of an epilepsy-linked GABA(A) receptor. Biochemistry. 45: 11632-41 |
| Ramakrishnan L, Hess GP. (2005) Picrotoxin inhibition mechanism of a gamma-aminobutyric acid A receptor investigated by a laser-pulse photolysis technique. Biochemistry. 44: 8523-32 |