Tiesong Shang, Ph.D.

2005 Medical College of Wisconsin, Milwaukee, WI, United States 
Neuroscience Biology, Molecular Biology, Cell Biology
"Tiesong Shang"
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B Kalyanaraman grad student 2005 Medical College of Wisconsin
 (Mitochondrial signaling in chemically-induced Parkinsonism: Free radical dependent and independent pathway.)
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Kotamraju S, Matalon S, Matsunaga T, et al. (2006) Upregulation of immunoproteasomes by nitric oxide: potential antioxidative mechanism in endothelial cells. Free Radical Biology & Medicine. 40: 1034-44
Kotamraju S, Kalivendi S, Shang T, et al. (2005) Nitric oxide, proteasomal function, and iron homeostasis--implications in aging and neurodegenerative diseases. Methods in Enzymology. 396: 526-34
Shang T, Kotamraju S, Zhao H, et al. (2005) Sepiapterin attenuates 1-methyl-4-phenylpyridinium-induced apoptosis in neuroblastoma cells transfected with neuronal NOS: role of tetrahydrobiopterin, nitric oxide, and proteasome activation. Free Radical Biology & Medicine. 39: 1059-74
Shang T, Joseph J, Hillard CJ, et al. (2005) Death-associated protein kinase as a sensor of mitochondrial membrane potential: role of lysosome in mitochondrial toxin-induced cell death. The Journal of Biological Chemistry. 280: 34644-53
Dhanasekaran A, Kotamraju S, Kalivendi SV, et al. (2004) Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis. The Journal of Biological Chemistry. 279: 37575-87
Shang T, Kotamraju S, Kalivendi SV, et al. (2004) 1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide. The Journal of Biological Chemistry. 279: 19099-112
Shang T, Uihlein AV, Van Asten J, et al. (2003) 1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3. Journal of Neurochemistry. 85: 358-67
Kalivendi SV, Kotamraju S, Cunningham S, et al. (2003) 1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide. The Biochemical Journal. 371: 151-64
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