Emily K. Griffiths, Ph.D.

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Immunology, Molecular Biology
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"Emily Griffiths"
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Josef M. Penninger grad student 2002 University of Toronto
 (Characterization of the in vivo roles of the adapter proteins ADAP and Cbl-3.)
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Publications

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Lynn BD, Li X, Hormuzdi SG, et al. (2018) E3 ubiquitin ligases LNX1 and LNX2 localize at neuronal gap junctions formed by connexin36 in rodent brain and molecularly interact with connexin36. The European Journal of Neuroscience
Griffiths EK, Sanchez O, Mill P, et al. (2003) Cbl-3-deficient mice exhibit normal epithelial development. Molecular and Cellular Biology. 23: 7708-18
Hara H, Wada T, Bakal C, et al. (2003) The MAGUK family protein CARD11 is essential for lymphocyte activation. Immunity. 18: 763-75
Griffiths EK, Penninger JM. (2002) Communication between the TCR and integrins: role of the molecular adapter ADAP/Fyb/Slap. Current Opinion in Immunology. 14: 317-22
Griffiths EK, Penninger JM. (2002) ADAP-ting TCR signaling to integrins. Science's Stke : Signal Transduction Knowledge Environment. 2002: re3
Krawczyk C, Oliveira-dos-Santos A, Sasaki T, et al. (2002) Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells. Immunity. 16: 331-43
Griffiths EK, Krawczyk C, Kong YY, et al. (2001) Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap. Science (New York, N.Y.). 293: 2260-3
Irie-Sasaki J, Sasaki T, Matsumoto W, et al. (2001) CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature. 409: 349-54
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