Gehad M. Subaiea, Ph.D.

Affiliations: 
2013 Pharmaceutical Sciences University of Rhode Island, Providence, RI, United States 
Area:
Pharmacology, Behavioral Psychology, Neuroscience Biology, Cognitive Psychology
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"Gehad Subaiea"
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Nasser Zawia grad student 2013 University of Rhode Island
 (Brain penetration of tolfenamic acid and its ability to enhance the cognitive functions and to lower amyloid pathology in animal mouse models of Alzheimer's disease.)
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Publications

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Bihaqi SW, Alansi B, Masoud AM, et al. (2018) Influence of Early Life Lead (Pb) exposure on α-Synuclein, GSK-3β and Caspase-3 mediated Tauopathy: Implications on Alzheimer's disease. Current Alzheimer Research
Masoud AM, Bihaqi SW, Alansi B, et al. (2018) Altered microRNA, mRNA, and Protein Expression of Neurodegeneration-Related Biomarkers and Their Transcriptional and Epigenetic Modifiers in a Human Tau Transgenic Mouse Model in Response to Developmental Lead Exposure. Journal of Alzheimer's Disease : Jad
Chang JK, Leso A, Subaiea GM, et al. (2018) Tolfenamic acid: A modifier of the tau protein and its role in cognition and tauopathy. Current Alzheimer Research
Adwan L, Subaiea GM, Basha R, et al. (2015) Tolfenamic acid reduces tau and CDK5 levels: implications for dementia and tauopathies. Journal of Neurochemistry. 133: 266-72
Subaiea GM, Ahmed AH, Adwan LI, et al. (2015) Reduction of amyloid-β deposition and attenuation of memory deficits by tolfenamic acid. Journal of Alzheimer's Disease : Jad. 43: 425-33
Ahmed AH, Subaiea GM, Eid A, et al. (2014) Pomegranate extract modulates processing of amyloid-β precursor protein in an aged Alzheimer's disease animal model. Current Alzheimer Research. 11: 834-43
Adwan L, Subaiea GM, Zawia NH. (2014) Tolfenamic acid downregulates BACE1 and protects against lead-induced upregulation of Alzheimer's disease related biomarkers. Neuropharmacology. 79: 596-602
Bihaqi SW, Bahmani A, Subaiea GM, et al. (2014) Infantile exposure to lead and late-age cognitive decline: relevance to AD. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 187-95
Subaiea GM, Adwan LI, Ahmed AH, et al. (2013) Short-term treatment with tolfenamic acid improves cognitive functions in Alzheimer's disease mice. Neurobiology of Aging. 34: 2421-30
Subaiea GM, Alansi BH, Serra DA, et al. (2011) The ability of tolfenamic acid to penetrate the brain: a model for testing the brain disposition of candidate Alzheimer's drugs using multiple platforms. Current Alzheimer Research. 8: 860-7
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