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Kathryn Partin

Affiliations: 
Colorado State University, Fort Collins, CO 
Area:
Neuroscience Biology
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"Kathryn Partin"
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Children

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Matthew A. Bedoukian grad student 2006 Colorado State
Autumn M. Weeks grad student 2006 Colorado State
Jonathan E. Harms grad student 2013 Colorado State

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Publications

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Caldwell N, Harms JE, Partin KM, et al. (2015) Rational Design of a Novel AMPA Receptor Modulator through a Hybridization Approach. Acs Medicinal Chemistry Letters. 6: 392-6
Partin KM. (2015) AMPA receptor potentiators: from drug design to cognitive enhancement. Current Opinion in Pharmacology. 20: 46-53
Weeks AM, Harms JE, Partin KM, et al. (2014) Functional insight into development of positive allosteric modulators of AMPA receptors. Neuropharmacology. 85: 57-66
Harms JE, Benveniste M, Kessler M, et al. (2014) A charge-inverting mutation in the "linker" region of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors alters agonist binding and gating kinetics independently of allosteric modulators. The Journal of Biological Chemistry. 289: 10702-14
Harms JE, Benveniste M, Maclean JK, et al. (2013) Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy. Neuropharmacology. 64: 45-52
Timm DE, Benveniste M, Weeks AM, et al. (2011) Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Molecular Pharmacology. 80: 267-80
Bedoukian MA, Whitesell JD, Peterson EJ, et al. (2008) The stargazin C terminus encodes an intrinsic and transferable membrane sorting signal. The Journal of Biological Chemistry. 283: 1597-600
Bedoukian MA, Weeks AM, Partin KM. (2006) Different domains of the AMPA receptor direct stargazin-mediated trafficking and stargazin-mediated modulation of kinetics. The Journal of Biological Chemistry. 281: 23908-21
Prescott C, Weeks AM, Staley KJ, et al. (2006) Kynurenic acid has a dual action on AMPA receptor responses. Neuroscience Letters. 402: 108-12
Jin R, Clark S, Weeks AM, et al. (2005) Mechanism of positive allosteric modulators acting on AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9027-36
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