Isamu Aiba, Ph.D.

Affiliations: 
2012 Biomedical Sciences University of New Mexico, Albuquerque, NM, United States 
Area:
Neuroscience Biology, Cell Biology
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"Isamu Aiba"
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C William Shuttleworth grad student 2012 Univ. of New Mexico
 (Studies on spreading depolarization in healthy and metabolically compromised brain tissues.)
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Publications

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Hatcher A, Yu K, Meyer J, et al. (2020) Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model. The Journal of Clinical Investigation
Aiba I. (2020) Adrenergic activation of cardiac preganglionic neurons in the Nucleus Ambiguus The Faseb Journal. 34: 1-1
Aiba I, Noebels J. (2019) Adrenergic agonist induces rhythmic firing in quiescent cardiac preganglionic neurons in nucleus ambiguous via activation of intrinsic membrane excitability. Journal of Neurophysiology
Aiba I, Wehrens XH, Noebels JL. (2016) Leaky RyR2 channels unleash a brainstem spreading depolarization mechanism of sudden cardiac death. Proceedings of the National Academy of Sciences of the United States of America
Bomben VC, Aiba I, Qian J, et al. (2016) Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 405-18
Aiba I, Noebels JL. (2015) Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models. Science Translational Medicine. 7: 282ra46
Seidel JL, Faideau M, Aiba I, et al. (2015) Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance. Glia. 63: 91-103
Aiba I, Shuttleworth CW. (2014) Characterization of inhibitory GABA-A receptor activation during spreading depolarization in brain slice. Plos One. 9: e110849
Aiba I, Shuttleworth CW. (2013) Hypoxia limits inhibitory effects of Zn2+ on spreading depolarizations. Plos One. 8: e75739
Aiba I, West AK, Sheline CT, et al. (2013) Intracellular dialysis disrupts Zn2+ dynamics and enables selective detection of Zn2+ influx in brain slice preparations. Journal of Neurochemistry. 125: 822-31
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