Howard Gutstein

The University of Texas Graduate School of Biomedical Sciences at Houston 
Neuroscience Biology
"Howard Gutstein"
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Puig S, Gutstein HB. (2023) Chronic Morphine Modulates PDGFR-β and PDGF-B Expression and Distribution in Dorsal Root Ganglia and Spinal Cord in Male Rats. Neuroscience. 519: 147-161
Barker KE, Lecznar AJ, Schumacher JM, et al. (2021) Subanalgesic morphine doses augment fentanyl analgesia by interacting with delta opioid receptors in male rats. Journal of Neuroscience Research
Puig S, Barker KE, Szott SR, et al. (2020) Spinal opioid tolerance depends upon platelet-derived growth factor receptor-β signaling, not mu-opioid receptor internalization. Molecular Pharmacology
Puig S, Donica CL, Gutstein HB. (2020) EGFR signaling causes morphine tolerance and mechanical sensitization in rats. Eneuro
Puig S, Gutstein HB. (2017) A "tail" of opioid receptor variants. The Journal of Clinical Investigation
Puig S, Gutstein HB. (2017) Opioids: keeping the good, eliminating the bad. Nature Medicine
Trang T, Al-Hasani R, Salvemini D, et al. (2015) Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13879-88
Wang Y, Barker K, Shi S, et al. (2012) Blockade of PDGFR-β activation eliminates morphine analgesic tolerance. Nature Medicine. 18: 385-7
Shurman J, Koob GF, Gutstein HB. (2010) Opioids, pain, the brain, and hyperkatifeia: a framework for the rational use of opioids for pain. Pain Medicine (Malden, Mass.). 11: 1092-8
Moulédous L, Díaz MF, Gutstein HB. (2007) Extracellular signal-regulated kinase (ERK) inhibition does not prevent the development or expression of tolerance to and dependence on morphine in the mouse. Pharmacology, Biochemistry, and Behavior. 88: 39-46
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