David McKinnon, Ph.D.

Affiliations:

Neurobiology & Behavior

Stony Brook University, Stony Brook, NY, United States

Area:

Ion channels, evolution, regulation of gene expression

Website:

http://neurobiology.informatics.sunysb.edu/graduate/faculty/mckinnon.html

Google:

"David McKinnon"

Bio:

David McKinnon received a B.Sc. in Physiology from the University of New South Wales, Australia, in 1983 and a Ph.D. in Physiology from the John Curtin School of Medical Research, Australian National University in 1987. Between 1987 and 1990, he was a Post-Doctoral Fellow at the Salk Institute and then at Washington University. In 1991 he joined the State University of New York at Stony Brook as Assistant Professor of Neurobiology and Behavior and was promoted to full professor in 2005.

Mean distance: 13.77 (cluster 11)

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Parents

Peter William Gage	grad student	1984-1987	ANU
Steve F. Heinemann	post-doc	1987-1989	SUNY Stony Brook
James Patrick	post-doc	1987-1989	Baylor College of Medicine
John Merlie	post-doc	1989-1990	Washington University

Children

Hong-Sheng Wang	grad student	1991-1996	University of Cincinnati
Wenmei Shi	grad student	1992-1998	SUNY Stony Brook
Zongming Pan	grad student	1994-2001	SUNY Stony Brook
Qinghong Yan	grad student	2007-2012	SUNY Stony Brook

Collaborators

BETA: Related publications

Publications

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McKinnon D, Rosati B. (2016) Transmural gradients in ion channel and auxiliary subunit expression. Progress in Biophysics and Molecular Biology
Kim M, McKinnon D, MacCarthy T, et al. (2015) Regulatory evolution and voltage-gated ion channel expression in squid axon: selection-mutation balance and fitness cliffs. Plos One. 10: e0120785
Wang HZ, Rosati B, Gordon C, et al. (2015) Inhibition of histone deacetylase (HDAC) by 4-phenylbutyrate results in increased junctional conductance between rat corpora smooth muscle cells. Frontiers in Pharmacology. 6: 9
Yan Q, Masson R, Ren Y, et al. (2012) Evolution of CpG island promoter function underlies changes in KChIP2 potassium channel subunit gene expression in mammalian heart. Proceedings of the National Academy of Sciences of the United States of America. 109: 1601-6
Rosati B, Yan Q, Lee MS, et al. (2011) Robust L-type calcium current expression following heterozygous knockout of the Cav1.2 gene in adult mouse heart. The Journal of Physiology. 589: 3275-88
Chung CY, Bien H, Sobie EA, et al. (2011) Hypertrophic phenotype in cardiac cell assemblies solely by structural cues and ensuing self-organization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 851-62
Yan Q, Masson R, Pritz MM, et al. (2011) Evolution of KChIP2 Gene Function is Localized Within the Core Promoter and 5’ UTR Biophysical Journal. 100
Rosati B, Dong M, Cheng L, et al. (2008) Evolution of ventricular myocyte electrophysiology. Physiological Genomics. 35: 262-72
Rosati B, Dun W, Hirose M, et al. (2007) Molecular basis of the T- and L-type Ca2+ currents in canine Purkinje fibres. The Journal of Physiology. 579: 465-71
Rosati B, Grau F, McKinnon D. (2006) Regional variation in mRNA transcript abundance within the ventricular wall. Journal of Molecular and Cellular Cardiology. 40: 295-302