Jeffrey J. Kovacs, Ph.D.

Affiliations: 
2005 Duke University, Durham, NC 
Area:
Molecular Biology, Pharmacology
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"Jeffrey Kovacs"
Mean distance: 21373.2
 

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Tso-Pang Yao grad student 2005 Duke
 (Characterization of novel domains and functions of HDAC6, a multifaceted deacetylase.)
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Publications

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Pai MT, Tzeng SR, Kovacs JJ, et al. (2007) Solution structure of the Ubp-M BUZ domain, a highly specific protein module that recognizes the C-terminal tail of free ubiquitin. Journal of Molecular Biology. 370: 290-302
Kovacs JJ, Cohen TJ, Yao TP. (2005) Chaperoning steroid hormone signaling via reversible acetylation. Nuclear Receptor Signaling. 3: e004
Murphy PJ, Morishima Y, Kovacs JJ, et al. (2005) Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone. The Journal of Biological Chemistry. 280: 33792-9
Kovacs JJ, Murphy PJ, Gaillard S, et al. (2005) HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor. Molecular Cell. 18: 601-7
Kovacs JJ, Hubbert C, Yao TP. (2004) The HDAC complex and cytoskeleton. Novartis Foundation Symposium. 259: 170-7; discussion 17
Kawaguchi Y, Kovacs JJ, McLaurin A, et al. (2003) The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell. 115: 727-38
Ito A, Kawaguchi Y, Lai CH, et al. (2002) MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. The Embo Journal. 21: 6236-45
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