Zhuohao He, Ph.D.

Affiliations: 
2013-2019 University of Pennsylvania, Philadelphia, PA, United States 
 2019- IRCBC_Chinese Academy of Sciences 
Area:
Neurodegeneration, Neurobiology
Website:
http://www.ircbc.ac.cn/team.php?id=190
Google:
"Zhuohao He"
Bio:

I have been trained as a neurobiologist since my graduate school at Institute of Neuroscience, Chinese Academy of Sciences, where I studies Ca2+ signaling pathways involved in neuronal physiological and pathological conditions. Since my postdoctoral training at University of Pennsylvania with Drs. Virginia Lee and John Trojanowski, I have learned neuropathy and autopsy, and have been more focused on Alzheimer’s disease (AD) and related neurodegenerative diseases from the view of misfolded proteins. I have developed several unique pathological-relevant AD mouse models, provided new insights on pathogenesis in multiple neurodegenerative diseases. Now I am leading an independent research group at IRCBC, CAS to continue the battle with such devastating diseases. My long term career goal is to develop diagnostic methods and therapeutic interventions for patients with early stages of AD and related diseases.

Mean distance: 16.44 (cluster 24)
 
SNBCP

Parents

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wang yizheng grad student 2005-2012 ION, CAS
Virginia Man-Yee Lee post-doc 2013- Penn
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Publications

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He Z, McBride JD, Xu H, et al. (2020) Transmission of tauopathy strains is independent of their isoform composition. Nature Communications. 11: 7
He Z, Guo JL, McBride JD, et al. (2017) Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation. Nature Medicine
He Z, Guo JL, McBride JD, et al. (2017) Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation. Nature Medicine
Narasimhan S, Guo JL, Changolkar L, et al. (2017) Pathological tau strains from human brains recapitulate the diversity of tauopathies in non-transgenic mouse brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Guo JL, Narasimhan S, Changolkar L, et al. (2016) Unique pathological tau conformers from Alzheimer's brains transmit tau pathology in nontransgenic mice. The Journal of Experimental Medicine
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