Matthew D. Lynes, Ph.D.

Affiliations: 
2012 Boston University, Boston, MA, United States 
Area:
Biochemistry, Nutrition
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Eric P. Widmaier grad student 2012 Boston University
 (Control of CD36 phosphorylation by global intestinal alkaline phosphatase mediates intestinal adaptation to high-fat diet.)
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Publications

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Townsend KL, Pritchard E, Coburn JM, et al. (2022) Silk Hydrogel-Mediated Delivery of Bone Morphogenetic Protein 7 Directly to Subcutaneous White Adipose Tissue Increases Browning and Energy Expenditure. Frontiers in Bioengineering and Biotechnology. 10: 884601
Lynes MD, Carlone DL, Townsend KL, et al. (2022) Telomerase Reverse Transcriptase Expression Marks a Population of Rare Adipose Tissue Stem Cells. Stem Cells (Dayton, Ohio). 40: 102-111
Angueira AR, Sakers AP, Holman CD, et al. (2021) Defining the lineage of thermogenic perivascular adipose tissue. Nature Metabolism
Shamsi F, Piper M, Ho LL, et al. (2021) Vascular smooth muscle-derived Trpv1 progenitors are a source of cold-induced thermogenic adipocytes. Nature Metabolism
Schlein C, Fischer AW, Sass F, et al. (2021) Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution. Cell Reports. 34: 108624
Wang CH, Lundh M, Fu A, et al. (2020) CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice. Science Translational Medicine. 12
Darcy J, Fang Y, McFadden S, et al. (2020) Integrated metabolomics reveals altered lipid metabolism in adipose tissue in a model of extreme longevity. Geroscience
Lynes MD, Tseng YH. (2020) Commentary on: "The Presence of Active Brown Adipose Tissue Determines Cold-Induced Energy Expenditure and Oxylipin Profiles in Humans". The Journal of Clinical Endocrinology and Metabolism. 105
Shamsi F, Xue R, Huang TL, et al. (2020) FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis. Nature Communications. 11: 1421
Sato M, Tsuji T, Yang K, et al. (2020) Cell-autonomous light sensitivity via Opsin3 regulates fuel utilization in brown adipocytes. Plos Biology. 18: e3000630
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