Markos Leggas, Ph.D.
Affiliations: | 2004 | University of Tennessee Health Science Center, Memphis, TN, United States |
Area:
Biomedical Engineering, PharmacologyGoogle:
"Markos Leggas"Mean distance: 35622
Parents
Sign in to add mentorClinton Stewart | grad student | 2004 | UTHSC | |
(Adenosine triphosphate binding cassette transporters in systemic and central nervous system disposition of topotecan.) |
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Publications
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Eckenrode JM, Mitra P, Rohr J, et al. (2019) Bioanalytical method for quantitative determination of mithramycin analogues in mouse plasma by HPLC-QTOF. Biomedical Chromatography : Bmc. e4544 |
Tang F, Tsakalozou E, Arnold SM, et al. (2019) Population pharmacokinetic analysis of AR-67, a lactone stable camptothecin analogue, in cancer patients with solid tumors. Investigational New Drugs |
Hayden RC, Hou C, Mitra P, et al. (2019) Abstract 2954: Mithramycin analogues disrupt ETS transcription factor DNA binding Cancer Research. 79: 2954-2954 |
Ye Q, Zhang Y, Cao Y, et al. (2018) Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects. Cell Chemical Biology |
Leggas M, Eckenrode J, Mitra P, et al. (2018) Abstract B043: Mithramycin-SA analogues with reduced toxicity for the treatment of ETS transcription factor-driven tumors Molecular Cancer Therapeutics. 17 |
Wang Y, Liu X, Pijut SS, et al. (2015) The combination of ezetimibe and ursodiol promotes fecal sterol excretion and reveals a G5G8-independent pathway for cholesterol elimination. Journal of Lipid Research. 56: 810-20 |
Eckenrode J, Horn J, Chen J, et al. (2015) Abstract 2628: Mithramycin analogs with reduced toxicity for EWS-FLI1 targeting Cancer Research. 75: 2628-2628 |
Penthala NR, Sonar VN, Horn J, et al. (2013) Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents. Medchemcomm. 4: 1073-1078 |
Hollis CP, Weiss HL, Leggas M, et al. (2013) Biodistribution and bioimaging studies of hybrid paclitaxel nanocrystals: lessons learned of the EPR effect and image-guided drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 12-21 |
Tsakalozou E, Adane ED, Kuo KL, et al. (2013) The effect of breast cancer resistance protein, multidrug resistant protein 1, and organic anion-transporting polypeptide 1B3 on the antitumor efficacy of the lipophilic camptothecin 7-t-butyldimethylsilyl-10-hydroxycamptothecin (AR-67) in vitro. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1404-13 |