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Mary K. Guyton, Ph.D.

Affiliations: 
2009 Medical University of South Carolina, Charleston, SC, United States 
Area:
Immunology
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"Mary Guyton"
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Naren L. Banik grad student 2009 MUSC
 (Calpain inhibition attenuates inflammatory and neurodegenerative events in animal models of multiple sclerosis.)

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Das A, Guyton MK, Smith A, et al. (2013) Calpain inhibitor attenuated optic nerve damage in acute optic neuritis in rats. Journal of Neurochemistry. 124: 133-46
Park S, Nozaki K, Guyton MK, et al. (2012) Calpain inhibition attenuated morphological and molecular changes in skeletal muscle of experimental allergic encephalomyelitis rats. Journal of Neuroscience Research. 90: 2134-45
Smith AW, Das A, Guyton MK, et al. (2011) Calpain inhibition attenuates apoptosis of retinal ganglion cells in acute optic neuritis. Investigative Ophthalmology & Visual Science. 52: 4935-41
Guyton MK, Das A, Samantaray S, et al. (2010) Calpeptin attenuated inflammation, cell death, and axonal damage in animal model of multiple sclerosis. Journal of Neuroscience Research. 88: 2398-408
Guyton MK, Brahmachari S, Das A, et al. (2009) Inhibition of calpain attenuates encephalitogenicity of MBP-specific T cells. Journal of Neurochemistry. 110: 1895-907
Das A, Guyton MK, Butler JT, et al. (2008) Activation of calpain and caspase pathways in demyelination and neurodegeneration in animal model of multiple sclerosis. Cns & Neurological Disorders Drug Targets. 7: 313-20
Das A, Guyton MK, Matzelle DD, et al. (2008) Time-dependent increases in protease activities for neuronal apoptosis in spinal cords of Lewis rats during development of acute experimental autoimmune encephalomyelitis. Journal of Neuroscience Research. 86: 2992-3001
Imam SA, Guyton MK, Haque A, et al. (2007) Increased calpain correlates with Th1 cytokine profile in PBMCs from MS patients. Journal of Neuroimmunology. 190: 139-45
Samantaray S, Knaryan VH, Guyton MK, et al. (2007) The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats. Neuroscience. 146: 741-55
Guyton MK, Sribnick EA, Ray SK, et al. (2005) A role for calpain in optic neuritis. Annals of the New York Academy of Sciences. 1053: 48-54
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