Stephen F. Traynelis

Rollins Research Center Emory University, Atlanta, GA 
NMDA receptors, Rare Mutations, Epilepsy, Stroke
"Stephen Traynelis"
Mean distance: 13.11 (cluster 11)


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Hanson JE, Yuan H, Perszyk RE, et al. (2023) Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Myers SJ, Yuan H, Perszyk RE, et al. (2023) Classification of missense variants in the N-methyl-D-aspartate receptor GRIN gene family as gain- or loss-of-function. Human Molecular Genetics
Nguyen TT, Camp CR, Doan JK, et al. (2023) GPR37L1 controls maturation and organization of cortical astrocytes during development. Glia
Xie L, McDaniel MJ, Perszyk RE, et al. (2023) Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening. Cellular and Molecular Life Sciences : Cmls. 80: 110
Harris LD, Regan MC, Myers SJ, et al. (2023) Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model. Acs Chemical Neuroscience
Tang W, Beckley JT, Zhang J, et al. (2023) Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions. Cellular and Molecular Life Sciences : Cmls. 80: 42
Zaczek R, Traynelis SF, Dingledine R, et al. (2023) Phase 1 Clinical Results for NP10679, a pH-sensitive GluN2B-selective N-methyl-d-aspartate Receptor Inhibitor. Clinical Pharmacology in Drug Development
Montanez-Miranda C, Perszyk RE, Harbin NH, et al. (2022) . Molecular Pharmacology
Chou TH, Kang H, Simorowski N, et al. (2022) Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Molecular Cell
Han W, Yuan H, Allen JP, et al. (2022) . The Journal of Pharmacology and Experimental Therapeutics
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