Ron A. Laskey
Affiliations: | University of Cambridge, Hutchison/MRC Research Centre |
Area:
Nuclear transport, mammalian DNA replicationWebsite:
http://www.hutchison-mrc.cam.ac.uk/Research/Ron_Laskey/index.htmlGoogle:
"Ron Laskey"Bio:
Discovered nuclear localization signals, coined the phrase "molecular chaperone", with Dirk Gorlich discovered importins.
Mean distance: 11.16
Parents
Sign in to add mentor| John B. Gurdon | grad student | (Neurotree) | |
| Lionel Crawford | post-doc | ICRF London |
Children
Sign in to add trainee| Richard Harland | grad student | Cambridge (Neurotree) | |
| Anna Philpott | grad student | Cambridge (Neurotree) | |
| J. Julian Blow | post-doc | University of Dundee | |
| William C. Earnshaw | post-doc | University of Cambridge, Hutchison/MRC Research Centre (Neurotree) | |
| Dirk Görlich | post-doc | Cambridge | |
| Torsten Krude | post-doc | ||
| Marcel Méchali | post-doc | University of Montpellier, France | |
| Michael A. Trakselis | post-doc | 2003-2006 | University of Cambridge, Hutchison/MRC Research Centre |
BETA: Related publications
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Publications
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| Wickramasinghe VO, Andrews R, Ellis P, et al. (2014) Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP. Nucleic Acids Research. 42: 5059-71 |
| Poole E, Bain M, Teague L, et al. (2012) The Cellular Protein MCM3AP Is Required for Inhibition of Cellular DNA Synthesis by the IE86 Protein of Human Cytomegalovirus Plos One. 7 |
| Wickramasinghe VO, McMurtrie PI, Mills AD, et al. (2010) mRNA export from mammalian cell nuclei is dependent on GANP. Current Biology : Cb. 20: 25-31 |
| Laskey R. (2005) Solving mysteries of DNA replication and frog cloning Cell. 123: 760-762 |
| Tachibana KK, Gonzalez MA, Guarguaglini G, et al. (2005) Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects Embo Reports. 6: 1052-1057 |
| Laskey R. (2005) The Croonian Lecture 2001 hunting the antisocial cancer cell: MCM proteins and their exploitation Philosophical Transactions of the Royal Society B: Biological Sciences. 360: 1119-1132 |
| McGeoch AT, Trakselis MA, Laskey RA, et al. (2005) Organization of the archaeal MCM complex on DNA and implications for the helicase mechanism Nature Structural and Molecular Biology. 12: 756-762 |
| Gonzalez MA, Tachibana KEK, Laskey RA, et al. (2005) Control of DNA replication and its potential clinical exploitation Nature Reviews Cancer. 5: 135-141 |
| Laskey RA, Madine MA. (2003) A rotary pumping model for helicase function of MCM proteins at a distance from replication forks Embo Reports. 4: 26-30 |
| Takei Y, Assenberg M, Tsujimoto G, et al. (2002) The MCM3 acetylase MCM3AP inhibits initiation, but not elongation, of DNA replication via interaction with MCM3 Journal of Biological Chemistry. 277: 43121-43125 |