Christopher James Donnelly, Ph.D.

Affiliations: 
Neurology Johns Hopkins University School of Medicine, Baltimore, MD, United States 
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Jeffery L. Twiss grad student 2011 University of Delaware
 (mRNA localization and the fate of the axon.)
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Publications

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Zhang K, Donnelly CJ, Haeusler AR, et al. (2015) The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature. 525: 56-61
Haidet-Phillips AM, Roybon L, Gross SK, et al. (2014) Gene profiling of human induced pluripotent stem cell-derived astrocyte progenitors following spinal cord engraftment. Stem Cells Translational Medicine. 3: 575-85
Haeusler AR, Donnelly CJ, Periz G, et al. (2014) C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature. 507: 195-200
Donnelly CJ, Zhang PW, Pham JT, et al. (2013) RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron. 80: 415-28
Yoo S, Kim HH, Kim P, et al. (2013) A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 3' untranslated region AU-rich regulatory element. Journal of Neurochemistry. 126: 792-804
Donnelly CJ, Park M, Spillane M, et al. (2013) Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3311-22
Donnelly CJ, Zhang PW, Pham JT, et al. (2013) RNA Toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention [Neuron, 79, (September 18, 2013), 1222-1231] Neuron. 80: 1102
Spillane M, Ketschek A, Donnelly CJ, et al. (2012) Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17671-89
Willis DE, Xu M, Donnelly CJ, et al. (2011) Axonal Localization of transgene mRNA in mature PNS and CNS neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14481-7
Donnelly CJ, Willis DE, Xu M, et al. (2011) Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity. The Embo Journal. 30: 4665-77
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