Christopher James Donnelly, Ph.D.
Affiliations: | Neurology | Johns Hopkins University School of Medicine, Baltimore, MD, United States |
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Sign in to add mentorJeffery L. Twiss | grad student | 2011 | University of Delaware | |
(mRNA localization and the fate of the axon.) |
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Publications
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Otte CG, Fortuna TR, Mann JR, et al. (2020) Optogenetic TDP-43 nucleation induces persistent insoluble species and progressive motor dysfunction in vivo. Neurobiology of Disease. 105078 |
Ortega JA, Daley EL, Kour S, et al. (2020) Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron |
Casci I, Krishnamurthy K, Kour S, et al. (2019) Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization. Nature Communications. 10: 5583 |
Mann JR, Gleixner AM, Mauna JC, et al. (2019) RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron |
Zhang K, Donnelly CJ, Haeusler AR, et al. (2015) The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature. 525: 56-61 |
Donnelly CJ, Grima JC, Sattler R. (2014) Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets? Neurodegenerative Disease Management. 4: 417-37 |
Haeusler AR, Donnelly CJ, Periz G, et al. (2014) C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature. 507: 195-200 |
Donnelly CJ, Zhang PW, Pham JT, et al. (2013) RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron. 80: 415-28 |
Yoo S, Kim HH, Kim P, et al. (2013) A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 3' untranslated region AU-rich regulatory element. Journal of Neurochemistry. 126: 792-804 |
Donnelly CJ, Park M, Spillane M, et al. (2013) Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3311-22 |