Sylvain Meloche

Affiliations: 
Université de Montréal, Montréal, Canada 
Area:
Microbiology Biology, Pharmacy
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"Sylvain Meloche"
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Publications

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Goupil E, Lacroix L, Brière J, et al. (2024) OSGN-1 is a conserved flavin-containing monooxygenase required to stabilize the intercellular bridge in late cytokinesis. Proceedings of the National Academy of Sciences of the United States of America. 121: e2308570121
Serwe G, Kachaner D, Gagnon J, et al. (2023) CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling. Nature Communications. 14: 3560
Pelletier B, Duhamel S, Tambutet G, et al. (2023) Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based p21 Degradation Screen. Acs Chemical Biology
Boudghene-Stambouli F, Soulez M, Ronkina N, et al. (2022) On the Therapeutic Potential of ERK4 in Triple-Negative Breast Cancer. Cancers. 15
Javary J, Goupil E, Soulez M, et al. (2022) Phosphoproteomic analysis identifies supervillin as an ERK3 substrate regulating cytokinesis and cell ploidy. Journal of Cellular Physiology
Houles T, Lavoie G, Nourreddine S, et al. (2022) CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. Nature Communications. 13: 6457
Soulez M, Tanguay PL, Dô F, et al. (2022) ERK3-MK5 signaling regulates myogenic differentiation and muscle regeneration by promoting FoxO3 degradation. Journal of Cellular Physiology
Guégan JP, Lapouge M, Voisin L, et al. (2022) Signaling by the tyrosine kinase Yes promotes liver cancer development. Science Signaling. 15: eabj4743
Mathien S, Tesnière C, Meloche S. (2021) Regulation of Mitogen-Activated Protein Kinase Signaling Pathways by the Ubiquitin-Proteasome System and Its Pharmacological Potential. Pharmacological Reviews. 73: 263-296
Aubert L, Nandagopal N, Steinhart Z, et al. (2020) Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer. Nature Communications. 11: 3701
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