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James J. Chambers, Ph.D.

Affiliations: 
2004-2007 MCB University of California, Berkeley, Berkeley, CA, United States 
 2008- Chemistry University of Massachusetts, Amherst, Amherst, MA 
Area:
Chemical Biology, Neuroscience
Website:
http://www.chamberslab.com/wp/
Google:
"James Chambers"
Mean distance: 14.72 (cluster 11)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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David E. Nichols grad student 1997-2002 Purdue
 (Use of conformationally-restricted analogues and homology modeling to provide insight into the nature of the 5-HT2A receptor agonist binding site.)
Richard H. Kramer post-doc 2004-2006 UC Berkeley

Children

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Joseph D. Reutt research assistant U Mass Amherst
Frances Rodríguez research assistant 2009 U Mass Amherst (Chemistry Tree)
Maya Marcus-Sells research assistant 2010-2011 U Mass Amherst (Chemistry Tree)
Matthew Stevens research assistant 2008-2012 U Mass Amherst
Kathryne Medeiros grad student 2009 U Mass Amherst
Amanda Hussey grad student 2009-2015 U Mass Amherst (Chemistry Tree)
Stephen McCarron grad student 2009-2015 U Mass Amherst (Chemistry Tree)
Vytla Devaiah post-doc 2008-2011 U Mass Amherst

Collaborators

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Dirk Trauner collaborator 2004-2006 UC Berkeley
BETA: Related publications

Publications

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McCarron ST, Chambers JJ. (2015) Modular chemical probes for visualizing and tracking endogenous ion channels. Neuropharmacology
Combs-Bachmann RE, Johnson JN, Vytla D, et al. (2015) Ligand-directed delivery of fluorophores to track native calcium-permeable AMPA receptors in neuronal cultures. Journal of Neurochemistry. 133: 320-9
Hussey AM, Chambers JJ. (2015) Methods to locate and track ion channels and receptors expressed in live neurons. Acs Chemical Neuroscience. 6: 189-98
Lin WC, Davenport CM, Mourot A, et al. (2014) Engineering a light-regulated GABAA receptor for optical control of neural inhibition. Acs Chemical Biology. 9: 1414-9
McCarron ST, Feliciano M, Johnson JN, et al. (2013) Photoinitiated release of an aziridinium ion precursor for the temporally controlled alkylation of nucleophiles. Bioorganic & Medicinal Chemistry Letters. 23: 2395-8
Hussey AM, Combs-Bachmann RE, Vytla D, et al. (2013) Development of an Activity Dependent, Photochemically-Released Tool for the Study of Calcium Permeable AMPA Receptors Biophysical Journal. 104: 499a
Vytla D, Combs-Bachmann RE, Hussey AM, et al. (2012) Prodrug approaches to reduce hyperexcitation in the CNS. Advanced Drug Delivery Reviews. 64: 666-85
Davenport CM, Lin W, Mourot A, et al. (2012) Optical Control of Neuronal Inhibition with Genetically Engineered Light Inhibited GABAA Receptors (Li-GABARs) Biophysical Journal. 102: 111a
Vytla D, Combs-Bachmann RE, Hussey AM, et al. (2011) Silent, fluorescent labeling of native neuronal receptors. Organic & Biomolecular Chemistry. 9: 7151-61
Jackman SL, Babai N, Chambers JJ, et al. (2011) A positive feedback synapse from retinal horizontal cells to cone photoreceptors. Plos Biology. 9: e1001057
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