Stuart S. Licht, PhD

Affiliations: 
2002-2008 Massachusetts Institute of Technology, Cambridge, MA, United States 
 2008-2010 Novartis, Basel, Basel-Stadt, France 
 2010- sanofi-aventis, St. Louis, MO, United States 
Website:
https://www.linkedin.com/pub/stuart-licht/7/57a/610
Google:
"Stuart Spencer Licht"
Bio:

Licht, Stuart S. A kinetically competent thiyl radical intermediate in ribonucleotide reduction , thesis MIT (1998)

Mean distance: 15.69 (cluster 11)
 
SNBCP

Parents

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JoAnne Stubbe grad student 1998 MIT (Chemistry Tree)
 (A kinetically competent thiyl radical intermediate in ribonucleotide reduction)
Peter G. Schultz post-doc 2000-2001 Scripps Research Institute (Chemistry Tree)
Anthony Auerbach post-doc 2001-2002 SUNY Buffalo

Children

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Amy Weeks research assistant MIT (Chemistry Tree)
Mathew C. Tantama grad student 2008 MIT
BETA: Related publications

Publications

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Koundinya M, Sudhalter J, Courjaud A, et al. (2018) Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers. Cell Chemical Biology
McManus J, He T, Gavigan JA, et al. (2018) A Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule Inhibitors of CD73 with Diverse Inhibition Modalities. Slas Discovery : Advancing Life Sciences R & D. 2472555217750386
Deng G, Shen J, Yin M, et al. (2015) Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. The Journal of Biological Chemistry. 290: 762-74
Lin WC, Licht S. (2014) Poly(ethylene glycol) as a scaffold for high-affinity open-channel blockers of the mouse nicotinic acetylcholine receptor. Plos One. 9: e112088
Zhang B, Yang G, Dai S, et al. (2014) Abstract 5468: SAR650984, a humanized anti-CD38 antibody potently modulates intracellular and extracellular nucleotide levels of cancer cells Cancer Research. 74: 5468-5468
Ding Z, Lennon A, Perron K, et al. (2014) Abstract 5448: PTK7 as a potential therapeutic target in ovarian cancer Cancer Research. 74: 5448-5448
Deng G, Licht S, Shen J, et al. (2014) Abstract 4746: Selective inhibition of mutant IDH1 via small molecule binding to the dimer interface Cancer Research. 74: 4746-4746
Choi KH, Licht S. (2012) ATP-sensitive potassium channels exhibit variance in the number of open channels below the limit predicted for identical and independent gating. Plos One. 7: e37399
Delaisi C, Meaux I, Dos-Santos O, et al. (2012) Abstract 4648: In vitro characterization of spiro-oxindole-based modulators of the MDM2-p53 interaction and their interspecies selectivity. Cancer Research. 72: 4648-4648
Licht S, Cao H, Li Z, et al. (2011) Abstract A226: Mechanism of action of iniparib: Stimulation of reactive oxygen species (ROS) production in an iniparib-sensitive breast cancer cell line. Molecular Cancer Therapeutics. 10
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