Stuart S. Licht, PhD

Affiliations: 
2002-2008 Massachusetts Institute of Technology, Cambridge, MA, United States 
 2008-2010 Novartis, Basel, Basel-Stadt, France 
 2010- sanofi-aventis, St. Louis, MO, United States 
Website:
https://www.linkedin.com/pub/stuart-licht/7/57a/610
Google:
"Stuart Spencer Licht"
Bio:

Licht, Stuart S. A kinetically competent thiyl radical intermediate in ribonucleotide reduction , thesis MIT (1998)

Mean distance: 15.69 (cluster 11)
 
SNBCP

Parents

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JoAnne Stubbe grad student 1998 MIT (Chemistry Tree)
 (A kinetically competent thiyl radical intermediate in ribonucleotide reduction)
Peter G. Schultz post-doc 2000-2001 Scripps Research Institute (Chemistry Tree)
Anthony Auerbach post-doc 2001-2002 SUNY Buffalo

Children

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Amy Weeks research assistant MIT (Chemistry Tree)
Mathew C. Tantama grad student 2008 MIT
BETA: Related publications

Publications

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McManus J, He T, Gavigan JA, et al. (2018) A Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule Inhibitors of CD73 with Diverse Inhibition Modalities. Slas Discovery : Advancing Life Sciences R & D. 2472555217750386
Deng G, Shen J, Yin M, et al. (2015) Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. The Journal of Biological Chemistry. 290: 762-74
Lin WC, Licht S. (2014) Poly(ethylene glycol) as a scaffold for high-affinity open-channel blockers of the mouse nicotinic acetylcholine receptor. Plos One. 9: e112088
Choi KH, Licht S. (2012) ATP-sensitive potassium channels exhibit variance in the number of open channels below the limit predicted for identical and independent gating. Plos One. 7: e37399
Tian-Yu J, Licht S, Pardee G, et al. (2010) Binding Rate Screen - a high-throughput assay in soluble lysate for prioritizing protein expression constructs. Analytical Biochemistry. 399: 276-83
Tantama M, Licht S. (2009) Functional equivalence of the nicotinic acetylcholine receptor transmitter binding sites in the open state. Biochimica Et Biophysica Acta. 1788: 936-44
Farbman ME, Gershenson A, Licht S. (2008) Role of a conserved pore residue in the formation of a prehydrolytic high substrate affinity state in the AAA+ chaperone ClpA. Biochemistry. 47: 13497-505
Tantama M, Licht S. (2008) Use of calculated cation-pi binding energies to predict relative strengths of nicotinic acetylcholine receptor agonists. Acs Chemical Biology. 3: 693-702
Tantama M, Lin WC, Licht S. (2008) An activity-based protein profiling probe for the nicotinic acetylcholine receptor. Journal of the American Chemical Society. 130: 15766-7
Jennings LD, Lun DS, Médard M, et al. (2008) ClpP hydrolyzes a protein substrate processively in the absence of the ClpA ATPase: mechanistic studies of ATP-independent proteolysis. Biochemistry. 47: 11536-46
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