Frederick W. Alt, PhD

Affiliations: 
Genetics Harvard University, Cambridge, MA, United States 
Area:
DNA repair, immunology, lymphoma
Website:
https://www.hms.harvard.edu/dms/bbs/fac/Alt.php
Google:
"Frederick W. Alt"
Bio:

https://genetics.hms.harvard.edu/faculty-staff/frederick-w-alt
https://www.hhmi.org/scientists/frederick-w-alt
http://searchworks.stanford.edu/view/761131

Mean distance: 14.7 (cluster 31)
 
SNBCP
Cross-listing: Chemistry Tree - Cell Biology Tree

Parents

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Robert T. Schimke grad student 1977 Stanford
 (The molecular mechanism of dihydrofolate reductase overproduction in methotrexate-resistant variants of culture murine cells)
David Baltimore post-doc 1982 MIT (Chemistry Tree)

Children

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George Yancopoulos grad student Columbia University Medical School
Yang Xu grad student 1994 Harvard (Stem Cell Tree)
Darryll D. Dudley grad student 2003 Harvard
Sean E. Rooney grad student 2003 Harvard
David H. Jung grad student 2006 Harvard
Cristian Boboila grad student 2005-2011 Harvard
Tingting Zhang-Kharas grad student 2005-2011 Harvard (Chemistry Tree)
Suprawee Tepsuporn grad student 2013 Harvard
Uttiya Basu post-doc Harvard
Huan Chen post-doc Harvard (Cell Biology Tree)
Bjoern Schwer post-doc
Ronald A. DePinho post-doc 1984-1988 Columbia
Angela K. Eggleston post-doc 1999-1999 Harvard Medical School - Boston Children's Hospital (Chemistry Tree)
Shan Zha post-doc 2004-2009 Harvard - Boston Children's Hospital (Chemistry Tree)
Richard L Frock post-doc 2010-2017 Harvard Medical School - Boston Children's Hospital (Cell Biology Tree)
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Publications

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Chen H, Zhang Y, Ye AY, et al. (2020) BCR selection and affinity maturation in Peyer's patch germinal centres. Nature
Tena A, Zhang Y, Kyritsis N, et al. (2020) Induction of recurrent break cluster genes in neural progenitor cells differentiated from embryonic stem cells in culture. Proceedings of the National Academy of Sciences of the United States of America
Tian M, McGovern K, Cheng HL, et al. (2020) Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models. Proceedings of the National Academy of Sciences of the United States of America
Bradley T, Kuraoka M, Yeh CH, et al. (2020) Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948
Wang M, Wei PC, Lim CK, et al. (2020) Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability. Cell Stem Cell
Saunders KO, Wiehe K, Tian M, et al. (2019) Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science (New York, N.Y.). 366
Zhang X, Zhang Y, Ba Z, et al. (2019) Fundamental roles of chromatin loop extrusion in antibody class switching. Nature
Zhang Y, Zhang X, Ba Z, et al. (2019) The fundamental role of chromatin loop extrusion in physiological V(D)J recombination. Nature
Shinkai Y, Koyasu S, Nakayama KI, et al. (2019) Pillars Article: Restoration of T Cell Development in RAG-2-Deficient Mice by Functional TCR Transgenes. . 1993. 259: 822-825. Journal of Immunology (Baltimore, Md. : 1950). 202: 1317-1320
Ratnaparkhe M, Wong JKL, Wei PC, et al. (2018) Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors. Nature Communications. 9: 4760
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