Brad S. Rothberg, Ph.D.

Affiliations: 
Biochemistry Temple University, Philadelphia, PA, United States 
Area:
K+ channels
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"Brad Rothberg"
Mean distance: 14.92 (cluster 46)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Bruce E. Hunter grad student 1994 University of Florida
 (Chronic ethanol treatment differentially affects muscarinic receptor responses in rat hippocampus)
Karl L. Magleby post-doc 1994-1999 University of Miami Miller School of Medicine
Gary Yellen post-doc 1999-2002 Harvard Medical School
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Publications

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Suma A, Granata D, Thomson AS, et al. (2020) Polyamine blockade and binding energetics in the MthK potassium channel. The Journal of General Physiology. 152
Rockman ME, Vouga AG, Rothberg BS. (2020) Molecular mechanism of BK channel activation by the smooth muscle relaxant NS11021. The Journal of General Physiology. 152
Li Q, Li Y, Wei H, et al. (2018) Molecular determinants of Ca2+ sensitivity at the intersubunit interface of the BK channel gating ring. Scientific Reports. 8: 509
Hooper R, Rothberg BS, Soboloff J. (2016) Sterol hindrance of Orai activation. Science Signaling. 9: fs4
Zhou Y, Wang X, Wang X, et al. (2015) STIM1 dimers undergo unimolecular coupling to activate Orai1 channels. Nature Communications. 6: 8395
McManus OB, Rothberg BS. (2014) An old probe sheds new light on BK channel pore structure. The Journal of General Physiology. 144: 499-501
Hooper R, Rothberg BS, Soboloff J. (2014) Neuronal STIMulation at rest. Science Signaling. 7: pe18
Thomson AS, Heer FT, Smith FJ, et al. (2014) Initial steps of inactivation at the K+ channel selectivity filter. Proceedings of the National Academy of Sciences of the United States of America. 111: E1713-22
Wang X, Wang Y, Zhou Y, et al. (2014) Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site. Nature Communications. 5: 3183
Smith FJ, Pau VP, Cingolani G, et al. (2013) Structural basis of allosteric interactions among Ca2+-binding sites in a K+ channel RCK domain. Nature Communications. 4: 2621
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