Manuela Polydoro, Ph.D.

Affiliations: 
Neurology MGH-Harvard 
Area:
Alzheimer's disease
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"Manuela Polydoro"
Mean distance: 14.13 (cluster 6)
 
SNBCP
Cross-listing: Alzheimer's Tree

Parents

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Pablo Castillo grad student Albert Einstein
Peter Davies grad student 2010 Yeshiva University
 (Deciphering neuronal dysfunction in Tau pathology.)
Bradley T. Hyman post-doc MGH-Harvard
BETA: Related publications

Publications

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Holtzman DM, Carrillo MC, Hendrix JA, et al. (2016) Tau: From research to clinical development. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Pooler AM, Polydoro M, Maury EA, et al. (2015) Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease. Acta Neuropathologica Communications. 3: 14
Saidi LJ, Polydoro M, Kay KR, et al. (2015) Carboxy terminus heat shock protein 70 interacting protein reduces tau-associated degenerative changes. Journal of Alzheimer's Disease : Jad. 44: 937-47
Spires-Jones TL, Friedman T, Pitstick R, et al. (2014) Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy. Neuroscience Letters. 562: 63-8
Polydoro M, Dzhala VI, Pooler AM, et al. (2014) Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model. Acta Neuropathologica. 127: 257-70
Ren Y, Lin WL, Sanchez L, et al. (2014) Endogenous tau aggregates in oligodendrocytes of rTg4510 mice induced by human P301L tau. Journal of Alzheimer's Disease : Jad. 38: 589-600
Pooler AM, Polydoro M, Wegmann S, et al. (2013) Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets. Alzheimer's Research & Therapy. 5: 49
Polydoro M, de Calignon A, Suárez-Calvet M, et al. (2013) Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13300-11
Pooler AM, Polydoro M, Wegmann SK, et al. (2013) Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology. The Journal of Comparative Neurology. 521: 4236-48
Crimins JL, Pooler A, Polydoro M, et al. (2013) The intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease. Ageing Research Reviews. 12: 757-63
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