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Krista Spiller

2006-2009 NIH/NIDA, Rockville, MD, United States 
 2009-2013 Neurobiology and Behavior Columbia University, New York, NY 
 2014- University of Pennsylvania, Philadelphia, PA, United States 
motor neuron diversity, neurodegeneration, glia, neuroregeneration
"Krista Spiller"

Mean distance: 15.56 (cluster 11)


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Eliot L. Gardner research assistant 2006-2009 NIH/NIDA
Christopher E. Henderson grad student 2014 Columbia
 (Using the natural resistance of motor neuron subpopulations to identify therapeutic targets in amyotrophic lateral sclerosis.)
Virginia Man-Yee Lee post-doc 2014-
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Spiller KJ, Bi GH, He Y, et al. (2019) Cannabinoid CB and CB receptor mechanisms underlie cannabis reward and aversion in rats. British Journal of Pharmacology
Spiller KJ, Khan T, Dominique MA, et al. (2018) Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice. Neurobiology of Disease
Thams S, Lowry ER, Larraufie MH, et al. (2018) A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress. Molecular Therapy : the Journal of the American Society of Gene Therapy
Spiller KJ, Restrepo CR, Khan T, et al. (2018) Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy. Nature Neuroscience
Spiller KJ, Restrepo CR, Khan T, et al. (2016) Progression of motor neuron disease is accelerated and the ability to recover is compromised with advanced age in rNLS8 mice. Acta Neuropathologica Communications. 4: 105
Spiller KJ, Cheung CJ, Restrepo CR, et al. (2016) Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7707-17
Walker AK, Spiller KJ, Ge G, et al. (2015) Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43. Acta Neuropathologica
Kaplan A, Spiller KJ, Towne C, et al. (2014) Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration. Neuron. 81: 333-48
Higley AE, Spiller K, Grundt P, et al. (2011) PG01037, a novel dopamine D3 receptor antagonist, inhibits the effects of methamphetamine in rats. Journal of Psychopharmacology (Oxford, England). 25: 263-73
Peng XQ, Xi ZX, Li X, et al. (2010) Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2564-78
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