Brian K. Kobilka
Affiliations: | Molecular & Cellular Physiology | Stanford University, Palo Alto, CA |
Area:
Adrenergic receptorsWebsite:
http://med.stanford.edu/kobilkalab/index.htmlGoogle:
"Brian Kobilka"Bio:
The Nobel Prize in Chemistry 2012 was awarded jointly to Robert J. Lefkowitz and Brian K. Kobilka "for studies of G-protein-coupled receptors"
Mean distance: 14.61 (cluster 11) | S | N | B | C | P |
Cross-listing: Chemistry Tree - Physiology Academic Tree
Parents
Sign in to add mentorRobert M. Carlson | research assistant | University of Minnesota Duluth (Chemistry Tree) | ||
Conrad E. Firling | research assistant | University of Minnesota Duluth (Physiology Academic Tree) | ||
(A medium for the maintenance of Chironomus tentans salivary glands in vitro.) | ||||
Robert J. Lefkowitz | post-doc | 1984-1989 | Duke |
Children
Sign in to add traineeAndrew Kruse | grad student | Stanford (Chemistry Tree) | |
Aashish Manglik | grad student | Stanford (Chemistry Tree) | |
Yoon Seok Kim | grad student | 2015- | Stanford |
Pejman Ghanouni | grad student | 2001 | Stanford (Chemistry Tree) |
Thomas P. Finsterbach | grad student | 2007 | Stanford (Chemistry Tree) |
Carl M. Hurt | grad student | 2007 | Stanford (Chemistry Tree) |
Juan J. Fung | grad student | 2009 | Stanford (Chemistry Tree) |
Daniel Hilger | post-doc | Stanford (Chemistry Tree) | |
Søren G.F. Rasmussen | post-doc | Stanford (Chemistry Tree) | |
Daniel M. Rosenbaum | post-doc | Stanford (Chemistry Tree) | |
Mark von Zastrow | post-doc | Stanford Medical School | |
John Janetzko | post-doc | 2017- | Stanford Medical School (Chemistry Tree) |
Haoqing Wang | post-doc | 2019- | Stanford (Chemistry Tree) |
Uwe Klein | post-doc | 1995-1998 | Stanford |
Peter Nollert | post-doc | 1999-2001 | Stanford (Chemistry Tree) |
Ka Young Chung | post-doc | 2008-2011 | Stanford |
Hideaki E. Kato | post-doc | 2014-2019 | Stanford School of Medicine (Chemistry Tree) |
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Publications
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Krishna Kumar K, Wang H, Habrian C, et al. (2024) Stepwise activation of a metabotropic glutamate receptor. Nature |
Zhao J, Elgeti M, O'Brien ES, et al. (2024) Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature |
Casiraghi M, Wang H, Brennan P, et al. (2024) Molecular insights into G protein specificity and biased agonism at the β -adrenergic receptor. Biorxiv : the Preprint Server For Biology |
Papasergi-Scott MM, Pérez-Hernández G, Batebi H, et al. (2024) Time-resolved cryo-EM of G-protein activation by a GPCR. Nature |
Heydenreich FM, Marti-Solano M, Sandhu M, et al. (2023) Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.). 382: eadh1859 |
Kumar KK, Wang H, Habrian C, et al. (2023) Step-wise activation of a Family C GPCR. Biorxiv : the Preprint Server For Biology |
Toyoda Y, Zhu A, Kong F, et al. (2023) Structural basis of α-adrenergic receptor activation and recognition by an extracellular nanobody. Nature Communications. 14: 3655 |
Zhao J, Elgeti M, O'Brien ES, et al. (2023) Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy. Biorxiv : the Preprint Server For Biology |
Krishna Kumar K, Robertson MJ, Thadhani E, et al. (2023) Structural basis for activation of CB1 by an endocannabinoid analog. Nature Communications. 14: 2672 |
Xu X, Shonberg J, Kaindl J, et al. (2023) Constrained catecholamines gain βAR selectivity through allosteric effects on pocket dynamics. Nature Communications. 14: 2138 |