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Amanda M. Shaw, Ph.D.

Affiliations: 
2004 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Pharmacology, Neuroscience Biology
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William J. Millard grad student 2004 UF Gainesville
 (Interactions of the growth hormone secretory axis and the central melanocortin system.)

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Publications

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Irani BG, Xiang Z, Yarandi HN, et al. (2011) Implication of the melanocortin-3 receptor in the regulation of food intake. European Journal of Pharmacology. 660: 80-7
Xiang Z, Litherland SA, Sorensen NB, et al. (2006) Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist. Biochemistry. 45: 7277-88
Proneth B, Xiang Z, Pogozheva ID, et al. (2006) Molecular mechanism of the constitutive activation of the L250Q human melanocortin-4 receptor polymorphism. Chemical Biology & Drug Design. 67: 215-29
Shaw AM, Irani BG, Moore MC, et al. (2005) Ghrelin-induced food intake and growth hormone secretion are altered in melanocortin 3 and 4 receptor knockout mice. Peptides. 26: 1720-7
Wilczynski A, Wang XS, Bauzo RM, et al. (2004) Structural characterization and pharmacology of a potent (Cys101-Cys119, Cys110-Cys117) bicyclic agouti-related protein (AGRP) melanocortin receptor antagonist. Journal of Medicinal Chemistry. 47: 5662-73
Wilczynski A, Wang XS, Joseph CG, et al. (2004) Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands. Journal of Medicinal Chemistry. 47: 2194-207
Joseph CG, Bauzo RM, Xiang Z, et al. (2003) Elongation studies of the human agouti-related protein (AGRP) core decapeptide (Yc[CRFFNAFC]Y) results in antagonism at the mouse melanocortin-3 receptor. Peptides. 24: 263-70
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