Evan P. Lebois, PhD
Affiliations: | Stanley Center for Psychiatric Disease | Broad Institute of Harvard and MIT |
Area:
Neuroscience Drug DiscoveryGoogle:
"Evan Lebois"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Jeffrey P. Conn | grad student | Vanderbilt | |
| Kurt L. Drickamer | grad student | Imperial College London (Chemistry Tree) | |
| Allan I. Levey | grad student | Emory | |
| Craig W. Lindsley | grad student | Vanderbilt (Chemistry Tree) | |
| Joseph R. Manns | grad student | Emory | |
| Erica Selva | grad student | University of Delaware |
Children
Sign in to add trainee| Chun Hu | research assistant | 2012-2015 | Emory |
| Leslie N. Aldrich | grad student | (Chemistry Tree) | |
| Emily Doucette | grad student | Harvard & MIT | |
| Matthew Hamm | grad student | University of Miami | |
| Jay Li | grad student | University of Michigan Medical School |
BETA: Related publications
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Publications
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| Galloway CR, Ravipati K, Singh S, et al. (2018) Hippocampal place cell dysfunction and the effects of muscarinic M receptor agonism in a rat model of Alzheimer's disease. Hippocampus |
| Lebois EP, Thorn C, Edgerton JR, et al. (2017) Muscarinic receptor subtype distribution in the central nervous system and relevance to aging and Alzheimer's disease. Neuropharmacology |
| Denny CA, Lebois E, Ramirez S. (2017) From Engrams to Pathologies of the Brain. Frontiers in Neural Circuits. 11: 23 |
| Lebois EP, Schroeder JP, Esparza TJ, et al. (2017) Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model. Acs Chemical Neuroscience |
| Lebois EP, Trimper JB, Hu C, et al. (2016) Effects of selective M1 muscarinic receptor activation on hippocampal spatial representations and neuronal oscillations. Acs Chemical Neuroscience |
| Galloway CR, Lebois EP, Shagarabi SL, et al. (2014) Effects of selective activation of M1 and M4 muscarinic receptors on object recognition memory performance in rats. Pharmacology. 93: 57-64 |
| Digby GJ, Utley TJ, Lamsal A, et al. (2012) Chemical modification of the M(1) agonist VU0364572 reveals molecular switches in pharmacology and a bitopic binding mode. Acs Chemical Neuroscience. 3: 1025-36 |
| Digby GJ, Noetzel MJ, Bubser M, et al. (2012) Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8532-44 |
| Melancon BJ, Gogliotti RD, Tarr JC, et al. (2012) Continued optimization of the MLPCN probe ML071 into highly potent agonists of the hM1 muscarinic acetylcholine receptor. Bioorganic & Medicinal Chemistry Letters. 22: 3467-72 |
| Lebois EP, Digby GJ, Sheffler DJ, et al. (2011) Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071. Bioorganic & Medicinal Chemistry Letters. 21: 6451-5 |