Barry M. Goldstein
Affiliations: | Biochemistry & Biophysics | University of Rochester, Rochester, NY |
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Children
Sign in to add trainee| Hong Li | grad student | 1990-1994 | Rochester (Chemistry Tree) |
| Kevin J. French | grad student | 2001 | Rochester |
| Michael D. Strickler | grad student | 2001 | Rochester |
| Dipesh Risal | grad student | 2003 | Rochester |
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Publications
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| Ceccarelli C, Liang ZX, Strickler M, et al. (2004) Crystal Structure and Amide H/D Exchange of Binary Complexes of Alcohol Dehydrogenase from Bacillus stearothermophilus: Insight into Thermostability and Cofactor Binding Biochemistry. 43: 5266-5277 |
| Pankiewicz KW, Patterson SE, Black PL, et al. (2004) Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target. Current Medicinal Chemistry. 11: 887-900 |
| Strickler M, Goldstein BM, Maxfield K, et al. (2003) Crystallographic studies on the complex behavior of nicotine binding to P450cam (CYP101). Biochemistry. 42: 11943-50 |
| Pankiewicz KW, Goldstein BM. (2003) NAD Analogues 18 — The Chemistry of Nucleoside and Dinucleotide Inhibitors of Inosine Monophosphate Dehydrogenase (IMPDH) Cheminform. 34 |
| Pankiewicz KW, Watanabe KA, Lesiak-Watanabe K, et al. (2002) The chemistry of nicotinamide adenine dinucleotide (NAD) analogues containing C-nucleosides related to nicotinamide riboside. Current Medicinal Chemistry. 9: 733-41 |
| French KJ, Rock DA, Rock DA, et al. (2002) Active site mutations of cytochrome p450cam alter the binding, coupling, and oxidation of the foreign substrates (R)- and (s)-2-ethylhexanol. Archives of Biochemistry and Biophysics. 398: 188-97 |
| Pankiewicz KW, Lesiak-Watanabe KB, Watanabe KA, et al. (2002) Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia. Journal of Medicinal Chemistry. 45: 703-12 |
| Clark JL, Patterson SE, Mason JC, et al. (2002) Novel inhibitors of inosine monophosphate dehydrogenase (IMPDH) Collection of Czechoslovak Chemical Communications. 5: 256-260 |
| French KJ, Strickler MD, Rock DA, et al. (2001) Benign synthesis of 2-ethylhexanoic acid by cytochrome P450cam: enzymatic, crystallographic, and theoretical studies. Biochemistry. 40: 9532-8 |
| Goldstein BM, Colby TD. (2000) Conformational constraints in NAD analogs: implications for dehydrogenase binding and specificity. Advances in Enzyme Regulation. 40: 405-426 |