Christopher D. Herzog, Ph.D.

Affiliations: 
Ceregene 
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"Christopher Herzog"
Mean distance: 15.37 (cluster 19)
 
SNBCP

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Tim Otto grad student 2000 Rutgers, New Brunswick
 (Regeneration of olfactory receptor neurons: Anatomical and behavioral effects of growth factor administration.)
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Publications

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Warren Olanow C, Bartus RT, Baumann TL, et al. (2015) Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial. Annals of Neurology. 78: 248-57
Bartus RT, Kordower JH, Johnson EM, et al. (2015) Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies. Neurobiology of Disease. 78: 162-71
Rafii MS, Baumann TL, Bakay RA, et al. (2014) A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 571-81
Herzog CD, Brown L, Kruegel BR, et al. (2013) Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120). Neurobiology of Disease. 58: 38-48
Bartus RT, Baumann TL, Siffert J, et al. (2013) Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients. Neurology. 80: 1698-701
Bartus RT, Baumann TL, Brown L, et al. (2013) Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating "clinical proof-of-concept" for AAV-neurturin (CERE-120) in Parkinson's disease. Neurobiology of Aging. 34: 35-61
Herzog CD, Bishop KM, Brown L, et al. (2011) Gene transfer provides a practical means for safe, long-term, targeted delivery of biologically active neurotrophic factor proteins for neurodegenerative diseases. Drug Delivery and Translational Research. 1: 361-82
Bartus RT, Brown L, Wilson A, et al. (2011) Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease. Neurobiology of Disease. 44: 38-52
Bartus RT, Herzog CD, Chu Y, et al. (2011) Bioactivity of AAV2-neurturin gene therapy (CERE-120): differences between Parkinson's disease and nonhuman primate brains. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 27-36
Herzog CD, Brown L, Gammon D, et al. (2009) Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease. Neurosurgery. 64: 602-12; discussion 6
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