T. Kendall Harden
Affiliations: | 1977-2014 | Pharmacology | University of North Carolina at Chapel Hill School of Medicine |
Website:
https://www.med.unc.edu/pharm/people/primaryfaculty/t-kendall-harden-1Google:
"T. Harden"Bio:
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Collaborators
Sign in to add collaborator| Kenneth A. Jacobson | collaborator | 1993-2016 | University of North Carolina at Chapel Hill School of Medicine |
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Publications
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| Boyer JL, Schachter JB, Sromek SM, et al. (2024) Avian and Human Homologues of the P2Y Receptor: Pharmacological, Signaling, and Molecular Properties. Drug Development Research. 39: 253-261 |
| Huang W, Wang X, Endo-Streeter S, et al. (2017) A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes. The Journal of Biological Chemistry |
| Charpentier TH, Waldo GL, Lowery-Gionta EG, et al. (2016) Potent and Selective Peptide-based Inhibition of the G protein Gαq. The Journal of Biological Chemistry |
| Sesma JI, Weitzer CD, Livraghi-Butrico A, et al. (2016) UDP-glucose promotes neutrophil recruitment in the lung. Purinergic Signalling |
| Junker A, Balasubramanian R, Ciancetta A, et al. (2016) Structure-Based Design of 3-(4-Aryl-1H-1,2,3-triazol-1-yl)-Biphenyl Derivatives as P2Y14 Receptor Antagonists. Journal of Medicinal Chemistry |
| Schrage R, Schmitz AL, Gaffal E, et al. (2015) The experimental power of FR900359 to study Gq-regulated biological processes. Nature Communications. 6: 10156 |
| Kiselev E, Balasubramanian R, Uliassi E, et al. (2015) Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y14 receptor. Bioorganic & Medicinal Chemistry Letters. 25: 4733-9 |
| Lazarowski ER, Harden TK. (2015) UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation. Molecular Pharmacology. 88: 151-60 |
| Kiselev E, Barrett MO, Katritch V, et al. (2014) Exploring a 2-naphthoic acid template for the structure-based design of P2Y14 receptor antagonist molecular probes. Acs Chemical Biology. 9: 2833-42 |
| Schmitz AL, Schrage R, Gaffal E, et al. (2014) A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation. Chemistry & Biology. 21: 890-902 |