Korrie Mack
Affiliations: | 2009- | University of Pennsylvania, Philadelphia, PA, United States |
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Parents
Sign in to add mentorIvan V. Korendovych | research assistant | 2012-2013 | Syracuse (Chemistry Tree) |
James Shorter | grad student | 2013- | Penn |
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Publications
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Mack KL, Kim H, Barbieri EM, et al. (2023) Tuning Hsp104 specificity to selectively detoxify α-synuclein. Molecular Cell |
Zhu G, Harischandra DS, Ghaisas S, et al. (2020) TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson's Disease. Cell Reports. 33: 108418 |
Wobst HJ, Mack KL, Brown DG, et al. (2020) The clinical trial landscape in amyotrophic lateral sclerosis-Past, present, and future. Medicinal Research Reviews |
Tariq A, Lin J, Jackrel ME, et al. (2019) Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity. Cell Reports. 28: 2080-2095.e6 |
Durie CL, Lin J, Scull NW, et al. (2019) Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases. Biophysical Journal |
March ZM, Mack KL, Shorter J. (2019) AAA+ Protein-Based Technologies to Counter Neurodegenerative Disease. Biophysical Journal |
Tariq A, Lin J, Noll MM, et al. (2018) Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain. Fems Yeast Research. 18 |
Weaver CL, Jackrel ME, Lin J, et al. (2018) Kinetic Mechanism of ATP-Dependent Disaggregating Motor Saccharomyces cerevisiae Hsp104 Biophysical Journal. 114: 553a |
Gates SN, Yokom AL, Lin J, et al. (2017) Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science (New York, N.Y.) |
Weaver CL, Duran EC, Mack KL, et al. (2017) Avidity for polypeptide binding by nucleotide-bound Hsp104 structures. Biochemistry |