Korrie Mack

Affiliations: 
2009- University of Pennsylvania, Philadelphia, PA, United States 
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"Korrie Mack"
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Ivan V. Korendovych research assistant 2012-2013 Syracuse (Chemistry Tree)
James Shorter grad student 2013- Penn
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Mack KL, Kim H, Barbieri EM, et al. (2023) Tuning Hsp104 specificity to selectively detoxify α-synuclein. Molecular Cell
Zhu G, Harischandra DS, Ghaisas S, et al. (2020) TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson's Disease. Cell Reports. 33: 108418
Wobst HJ, Mack KL, Brown DG, et al. (2020) The clinical trial landscape in amyotrophic lateral sclerosis-Past, present, and future. Medicinal Research Reviews
Tariq A, Lin J, Jackrel ME, et al. (2019) Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity. Cell Reports. 28: 2080-2095.e6
Durie CL, Lin J, Scull NW, et al. (2019) Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases. Biophysical Journal
March ZM, Mack KL, Shorter J. (2019) AAA+ Protein-Based Technologies to Counter Neurodegenerative Disease. Biophysical Journal
Tariq A, Lin J, Noll MM, et al. (2018) Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain. Fems Yeast Research. 18
Weaver CL, Jackrel ME, Lin J, et al. (2018) Kinetic Mechanism of ATP-Dependent Disaggregating Motor Saccharomyces cerevisiae Hsp104 Biophysical Journal. 114: 553a
Gates SN, Yokom AL, Lin J, et al. (2017) Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science (New York, N.Y.)
Weaver CL, Duran EC, Mack KL, et al. (2017) Avidity for polypeptide binding by nucleotide-bound Hsp104 structures. Biochemistry
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