JiaBei Lin
Affiliations: | 2016- | University of Pennsylvania, Philadelphia, PA, United States |
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Parents
Sign in to add mentor| Aaron L. Lucius | grad student | University of Alabama Birmingham School of Medicine (Chemistry Tree) | |
| James Shorter | post-doc | 2016- | Penn |
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Publications
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| Guo L, Mann JR, Mauna JC, et al. (2023) Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains. Biorxiv : the Preprint Server For Biology |
| Mack KL, Kim H, Barbieri EM, et al. (2023) Tuning Hsp104 specificity to selectively detoxify α-synuclein. Molecular Cell |
| Lin J, Shorter J, Lucius AL. (2022) AAA+ proteins: one motor, multiple ways to work. Biochemical Society Transactions |
| Huang L, Agrawal T, Zhu G, et al. (2021) DAXX represents a new type of protein-folding enabler. Nature |
| March ZM, Sweeney K, Kim H, et al. (2020) Therapeutic genetic variation revealed in diverse Hsp104 homologs. Elife. 9 |
| Lopez KE, Rizo AN, Tse E, et al. (2020) Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nature Structural & Molecular Biology |
| Ye X, Lin J, Mayne L, et al. (2020) Structural and kinetic basis for the regulation and potentiation of Hsp104 function. Proceedings of the National Academy of Sciences of the United States of America |
| Jones RD, Enam C, Ibarra R, et al. (2019) The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate. Molecular Biology of the Cell. mbcE18020121 |
| Tariq A, Lin J, Jackrel ME, et al. (2019) Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity. Cell Reports. 28: 2080-2095.e6 |
| Rizo AN, Lin J, Gates SN, et al. (2019) Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase. Nature Communications. 10: 2393 |