Megumi Yamashita

Pharmacology Northwestern University, Evanston, IL 
"Megumi Yamashita"
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Yeung PS, Yamashita M, Prakriya M. (2023) A pathogenic human Orai1 mutation unmasks STIM1-independent rapid inactivation of Orai1 channels. Elife. 12
Tsujikawa S, DeMeulenaere KE, Centeno MV, et al. (2023) Regulation of neuropathic pain by microglial Orai1 channels. Science Advances. 9: eade7002
Letizia M, Wang YH, Kaufmann U, et al. (2022) Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease. Embo Molecular Medicine. e15687
Shrestha N, Hye-Ryong Shim A, Maneshi MM, et al. (2022) Mapping interactions between the CRAC activation domain and CC1 that regulate the activity of the ER Ca sensor STIM1. The Journal of Biological Chemistry. 102157
Erdogmus S, Concepcion AR, Yamashita M, et al. (2022) Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca channel function. Nature Communications. 13: 2033
Yamashita M, Prakriya M. (2021) Interrogating permeation and gating of Orai channels using chemical modification of cysteine residues. Methods in Enzymology. 652: 213-239
Maneshi MM, Toth AB, Ishii T, et al. (2021) Orai1 channels are essential for amplification of glutamate-evoked Ca2+ signals in dendritic spines to regulate working and associative memory. Cell Reports. 34: 108911
Prakriya M, Yeung PS, Yamashita M. (2021) An open pore structure of the Orai channel, finally. Cell Calcium. 94: 102366
Maneshi MM, Toth AB, Ishii T, et al. (2020) Orai1 Channels Are Essential for Amplification of Glutamate-Evoked Ca Signals in Dendritic Spines to Regulate Working and Associative Memory. Cell Reports. 33: 108464
Yeung PS, Ing CE, Yamashita M, et al. (2020) A sulfur-aromatic gate latch is essential for opening of the Orai1 channel pore. Elife. 9
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