Sascha R.A. Alles, Ph.D.

Affiliations: 
2019- Department of Anesthesiology and Critical Care Medicine University of New Mexico School of Medicine 
Area:
Chronic pain, nociception, ion channels
Website:
alleslab.com
Google:
"Sascha Alles"
Bio:

Dr. Alles completed his undergraduate degree in Biochemistry at Imperial College London and his PhD in Neuroscience at the University of Alberta with Prof Peter Smith, studying mechanisms of the gabapentinoid drugs for neuropathic pain. He then went on to complete Postdoctoral Fellowships at the University of British Columbia with Professor Terry Snutch and at University College London with Professor John Wood. His work focusses on understanding chronic pain mechanisms and ion channel biology and has facilitated unique insights into novel therapeutics for treating pain, such as those impacting the ion channel NaV1.7.

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Parents

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Peter A. Smith grad student 2011-2016 University of Alberta
Terry P. Snutch post-doc 2016-2017 UBC
John N. Wood post-doc 2017-2019 University College London

Collaborators

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Karin Westlund High collaborator 2019- University of New Mexico School of Medicine
Michael Blake Hoppa collaborator 2020- Dartmouth
Rajesh Khanna collaborator 2020- University of Arizona
Aubin Moutal collaborator 2020- University of Arizona
Ian Winship collaborator 2014-2016 University of Alberta
Glen Baker collaborator 2015-2017 University of Alberta
Brian A. Macvicar collaborator 2016-2017 UBC
Marco Beato collaborator 2018-2019 UCL
BETA: Related publications

Publications

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Ehsanian R, Koshkin E, Goins AE, et al. (2021) Pre- and Post-Interventional Changes in Physiological Profiles in a Patient Presenting With Opioid Withdrawal After Intrathecal Drug Delivery System Failure Related to Assumed Catheter Microfracture Cureus. 13: e14835
Garcia-Caballero A, Zhang FX, Hodgkinson V, et al. (2018) T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B. Molecular Brain. 11: 24
Cain SM, Bohnet B, LeDue J, et al. (2017) In vivo imaging reveals that pregabalin inhibits cortical spreading depression and propagation to subcortical brain structures. Proceedings of the National Academy of Sciences of the United States of America
Alles SR, Bandet MV, Eppler K, et al. (2016) Acute anti-allodynic action of gabapentin in dorsal horn and primary somatosensory cortex: Correlation of behavioural and physiological data. Neuropharmacology
Alles SR, Smith PA. (2016) The Anti-Allodynic Gabapentinoids: Myths, Paradoxes, and Acute Effects. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry
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