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Christophe Pignier, PhD

Affiliations: 
Perre Fabre Mediicament 
Area:
Drug research
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"Christophe Pignier"
Mean distance: 16.95 (cluster 16)
 		SNBCP
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Ernst Niggli grad student 1999-2002 University of Bern

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Pignier C, Rougier JS, Vié B, et al. (2010) Selective inhibition of persistent sodium current by F 15845 prevents ischaemia-induced arrhythmias. British Journal of Pharmacology. 161: 79-91
Le Grand B, Pignier C, Létienne R, et al. (2009) Na+ currents in cardioprotection: better to be late. Journal of Medicinal Chemistry. 52: 4149-60
Vacher B, Pignier C, Létienne R, et al. (2009) F 15845 inhibits persistent sodium current in the heart and prevents angina in animal models. British Journal of Pharmacology. 156: 214-25
Pignier C, Le Grand B. (2008) Letter by Pignier and Le Grand regarding article "Acute administration of fish oil inhibits triggered activity in isolated myocytes from rabbits and patients with heart failure". Circulation. 118: e69; author reply e7
Le Grand B, Pignier C, Létienne R, et al. (2008) Sodium late current blockers in ischemia reperfusion: is the bullet magic? Journal of Medicinal Chemistry. 51: 3856-66
Pinet C, Algalarrondo V, Sablayrolles S, et al. (2008) Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes. Molecular Pharmacology. 73: 1622-31
Keller M, Pignier C, Egger M, et al. (2007) F90927: a new member in the class of cardioactive steroids. Cardiovascular Drug Reviews. 25: 210-20
Pignier C, Revenaz C, Rauly-Lestienne I, et al. (2007) Direct protective effects of poly-unsaturated fatty acids, DHA and EPA, against activation of cardiac late sodium current: a mechanism for ischemia selectivity. Basic Research in Cardiology. 102: 553-64
Keller M, Pignier C, Santelli M, et al. (2006) Agonist specific L-type Ca(2+)-current stimulation in ventricular myocytes by a novel steroid-like compound. Cell Calcium. 39: 425-33
Pignier C, Keller M, Vié B, et al. (2006) A novel steroid-like compound F90927 exerting positive-inotropic effects in cardiac muscle. British Journal of Pharmacology. 147: 772-82
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