Alpa Khatri

Affiliations: 
Rollins Research Center, Emory University 
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"Alpa Khatri"
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Perszyk RE, Swanger SA, Shelley C, et al. (2020) Biased modulators of NMDA receptors control channel opening and ion selectivity. Nature Chemical Biology
Bhattacharya S, Khatri A, Swanger SA, et al. (2018) Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells. Neuron. 99: 315-328.e5
Perszyk RE, DiRaddo JO, Strong KL, et al. (2016) GluN2D-containing NMDA receptors mediate synaptic transmission in hippocampal interneurons and regulate interneuron activity. Molecular Pharmacology
Zimmerman SS, Khatri A, Garnier-Amblard EC, et al. (2015) Correction to "Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators". Journal of Medicinal Chemistry. 58: 2862
Khatri A, Burger PB, Swanger SA, et al. (2014) Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator. Molecular Pharmacology. 86: 548-60
Santangelo Freel RM, Ogden KK, Strong KL, et al. (2014) Correction to Synthesis and Structure Activity Relationship of Tetrahydroisoquinoline-Based Potentiators of GluN2C and GluN2D Containing N-Methyl-d-aspartate Receptors. Journal of Medicinal Chemistry. 57: 4975
Zimmerman SS, Khatri A, Garnier-Amblard EC, et al. (2014) Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators. Journal of Medicinal Chemistry. 57: 2334-56
Ogden KK, Khatri A, Traynelis SF, et al. (2014) Potentiation of GluN2C/D NMDA receptor subtypes in the amygdala facilitates the retention of fear and extinction learning in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 625-37
Acker TM, Khatri A, Vance KM, et al. (2013) Structure-activity relationships and pharmacophore model of a noncompetitive pyrazoline containing class of GluN2C/GluN2D selective antagonists. Journal of Medicinal Chemistry. 56: 6434-56
Santangelo Freel RM, Ogden KK, Strong KL, et al. (2013) Synthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptors. Journal of Medicinal Chemistry. 56: 5351-81
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