Thomas J. Melia, Ph.D.

Cell Biology Yale University School of Medicine, New Haven, CT 
Macroautophagy, autophagy
"Thomas Melia"
Mean distance: 16.94 (cluster 11)
Cross-listing: Cell Biology Tree


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Theodore G. Wensel grad student 1992-1999 Baylor
 (Now at Yale)
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Horenkamp FA, Kauffman KJ, Kohler LJ, et al. (2015) The Legionella Anti-autophagy Effector RavZ Targets the Autophagosome via PI3P- and Curvature-Sensing Motifs. Developmental Cell. 34: 569-76
Dancourt J, Melia TJ. (2014) Lipidation of the autophagy proteins LC3 and GABARAP is a membrane-curvature dependent process. Autophagy. 10: 1470-1
Nath S, Dancourt J, Shteyn V, et al. (2014) Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3. Nature Cell Biology. 16: 415-24
Choy A, Dancourt J, Mugo B, et al. (2012) The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation. Science (New York, N.Y.). 338: 1072-6
Johnson CW, Melia TJ, Yamamoto A. (2012) Modulating macroautophagy: a neuronal perspective. Future Medicinal Chemistry. 4: 1715-31
Jotwani A, Richerson DN, Motta I, et al. (2012) Approaches to the study of Atg8-mediated membrane dynamics in vitro. Methods in Cell Biology. 108: 93-116
Xu Y, Melia TJ, Toomre DK. (2011) Using light to see and control membrane traffic. Current Opinion in Chemical Biology. 15: 822-30
Klionsky DJ, Baehrecke EH, Brumell JH, et al. (2011) A comprehensive glossary of autophagy-related molecules and processes (2nd edition). Autophagy. 7: 1273-94
Shi L, Kümmel D, Coleman J, et al. (2011) Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex. Molecular Biology of the Cell. 22: 4150-60
Nair U, Jotwani A, Geng J, et al. (2011) SNARE proteins are required for macroautophagy. Cell. 146: 290-302
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