Laëtitia Miguel
Affiliations: | University of Rouen |
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Parents
Sign in to add mentor| Dominique Campion | grad student | 2012 | University of Rouen | |
| (Caractérisation des mécanismes physiopathologiques des protéines TDP-43 et FUS dans les maladies neurodégénératives en utilisant la drosophile comme modèle d'étude) | ||||
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Publications
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| Miguel L, Gervais J, Nicolas G, et al. (2023) SorLA Protective Function Is Restored by Improving SorLA Protein Maturation in a Subset of Alzheimer's Disease-Associated SORL1 Missense Variants. Journal of Alzheimer's Disease : Jad |
| Miguel L, Rovelet-Lecrux A, Chambon P, et al. (2022) Generation of 17q21.31 duplication iPSC-derived neurons as a model for primary tauopathies. Stem Cell Research. 61: 102762 |
| Rovelet-Lecrux A, Feuillette S, Miguel L, et al. (2021) Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease. Acta Neuropathologica Communications. 9: 196 |
| Wallon D, Boluda S, Rovelet-Lecrux A, et al. (2021) Clinical and neuropathological diversity of tauopathy in MAPT duplication carriers. Acta Neuropathologica |
| Miguel L, Frebourg T, Campion D, et al. (2020) Moderate Overexpression of Tau in Drosophila Exacerbates Amyloid-β-Induced Neuronal Phenotypes and Correlates with Tau Oligomerization. Journal of Alzheimer's Disease : Jad |
| Miguel L, Rovelet-Lecrux A, Feyeux M, et al. (2019) Detection of all adult Tau isoforms in a 3D culture model of iPSC-derived neurons. Stem Cell Research. 40: 101541 |
| Pons M, Prieto S, Miguel L, et al. (2018) Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila. Acta Neuropathologica Communications. 6: 138 |
| Miguel L, Avequin T, Pons M, et al. (2018) FTLD/ALS-linked TDP-43 mutations do not alter TDP-43's ability to self-regulate its expression in Drosophila. Brain Research |
| Pons M, Miguel L, Miel C, et al. (2017) Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model. Human Molecular Genetics. 26: 3396-3408 |
| Khalil B, Cabirol-Pol MJ, Miguel L, et al. (2017) Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies. Neurobiology of Aging. 54: 71-83 |