Dilshan S. Harischandra

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Neurodegenerative disease, Protein aggregation, metal neurotoxicity
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"Dilshan Harischandra"
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Collaborators

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Matthew Neal collaborator
Nikhil Panicker collaborator
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Publications

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Harischandra DS, Rokad D, Ghaisas S, et al. (2019) Enhanced differentiation of human dopaminergic neuronal cell model for preclinical translational research in Parkinson's disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165533
Harischandra DS, Ghaisas S, Zenitsky G, et al. (2019) Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation. Frontiers in Neuroscience. 13: 654
Panicker N, Sarkar S, Harischandra DS, et al. (2019) Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia. The Journal of Experimental Medicine
Harischandra DS, Rokad D, Neal ML, et al. (2019) Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein. Science Signaling. 12
Sarkar S, Rokad D, Malovic E, et al. (2019) Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells. Science Signaling. 12
Neal M, Luo J, Harischandra DS, et al. (2018) Prokineticin-2 promotes chemotaxis and alternative A2 reactivity of astrocytes. Glia
Sarkar S, Malovic E, Harischandra DS, et al. (2017) Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes. Neurotoxicology
Harischandra DS, Ghaisas S, Rokad D, et al. (2017) Exosomes in Toxicology: Relevance to Chemical Exposure and Pathogenesis of Environmentally Linked Diseases. Toxicological Sciences : An Official Journal of the Society of Toxicology
Harischandra DS, Ghaisas S, Rokad D, et al. (2017) Environmental Neurotoxicant Manganese Regulates Exosome-mediated Extracellular miRNAs in Cell Culture Model of Parkinson's Disease: Relevance to α-Synuclein Misfolding in Metal Neurotoxicity. Neurotoxicology
Rokad D, Ghaisas S, Harischandra DS, et al. (2016) Role of Neurotoxicants and Traumatic Brain Injury in α-Synuclein Protein Misfolding and Aggregation. Brain Research Bulletin
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