Rebecca J. Chan, MD/PhD

Affiliations: 
Pediatric  Indiana University School of Medicine, Indianapolis, IN, United States 
Area:
Pediatric Medicine, Noonan Syndrome
Google:
"Rebecca Chan"
Mean distance: 17.93 (cluster 11)
 
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Publications

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Ramdas B, Yuen LD, Palam LR, et al. (2022) Inhibition of BTK and PI3Kδ impairs the development of Human JMML Stem and Progenitor cells. Molecular Therapy : the Journal of the American Society of Gene Therapy
Tarnawsky SP, Yu WM, Qu CK, et al. (2018) Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice. Oncotarget. 9: 21831-21843
Deng L, Richine BM, Virts EL, et al. (2018) Rapid development of myeloproliferative neoplasm in mice withmutation and haploinsufficient for. Oncotarget. 9: 6055-6061
Patel R, Ramdas B, Deng L, et al. (2018) Combined Pharmacological Inhibition of Bruton's Tyrosine Kinase (BTK) and Phosphoinositide 3-Kinase (PI3K) p110δ Rescues Monocytosis, Thrombocytopenia, and Splenomegaly in a Genetic Mouse Model for JMML Blood. 132: 2623-2623
Deng L, Chan RJ. (2017) Cleaning up the environment in juvenile myelomonocytic leukemia. Translational Cancer Research. 6: S36-S38
Deng L, Virts EL, Kapur R, et al. (2017) Pharmacologic inhibition of PI3K p110δ in mutant Shp2E76K-expressing mice. Oncotarget. 8: 84776-84781
Tarnawsky SP, Yoshimoto M, Deng L, et al. (2017) Yolk Sac Erythromyeloid Progenitors Expressing Gain Of Function PTPN11 Have Functional Features Of JMML But Are Not Sufficient To Cause Disease In Mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists
Tarnawsky SP, Chan RJ, Yoder MC. (2017) Mice expressing KrasG12D in hematopoietic multipotent progenitor cells develop neonatal myeloid leukemia. The Journal of Clinical Investigation
O'Leary HA, Capitano M, Cooper S, et al. (2017) DPP4 truncated GM-CSF & IL-3 manifest distinct receptor binding & regulatory functions compared to their full length forms. Leukemia
Liu W, Yu WM, Zhang J, et al. (2016) Inhibition of the Gab2/PI3K/mTOR signaling ameliorates myeloid malignancy caused by Ptpn11 (Shp2) gain-of-function mutations. Leukemia
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