Hai M. Nguyen, Ph.D.
Affiliations: | University of California, Irvine, Irvine, CA |
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"Hai Nguyen"Mean distance: 15.37 (cluster 11) | S | N | B | C | P |
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Peer Wulff | grad student | UC Irvine | ||
| Alan L. Goldin | grad student | 2009 | UC Irvine | |
| (Identification of molecular determinants responsible for isoform-specific function of voltage -gated sodium channels.) | ||||
| George Chandy | post-doc | UC Irvine | ||
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Publications
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| Nguyen PT, Nguyen HM, Wagner KM, et al. (2022) Computational design of peptides to target Na1.7 channel with high potency and selectivity for the treatment of pain. Elife. 11 |
| Srinivasan SR, Huang H, Chang WC, et al. (2022) Discovery of novel activators of large-conductance calcium-activated potassium channels for the treatment of cerebellar ataxia. Molecular Pharmacology |
| Orfali R, Nam YW, Nguyen HM, et al. (2022) Channelopathy-causing mutations in the SA/SB and HA/HB helices of K2.3 and K3.1 channels alter their apparent Ca sensitivity. Cell Calcium. 102: 102538 |
| Ramesha S, Rayaprolu S, Bowen CA, et al. (2021) Unique molecular characteristics and microglial origin of Kv1.3 channel-positive brain myeloid cells in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Fomina AF, Nguyen HM, Wulff H. (2021) Kv1.3 inhibition attenuates neuroinflammation through disruption of microglial calcium signaling. Channels (Austin, Tex.). 15: 67-78 |
| Ong ST, Bajaj S, Tanner MR, et al. (2020) Modulation of Lymphocyte Potassium Channel K1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin. Acs Pharmacology & Translational Science. 3: 720-736 |
| Sarkar S, Nguyen HM, Malovic E, et al. (2020) Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease. The Journal of Clinical Investigation |
| Nguyen HM, di Lucente J, Chen YJ, et al. (2020) Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4-mediated calcium entry in microglia. Glia |
| Jin LW, Lucente JD, Nguyen HM, et al. (2019) Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease. Annals of Clinical and Translational Neurology. 6: 723-738 |
| Brown BM, Nguyen HM, Wulff H. (2019) Recent advances in our understanding of the structure and function of more unusual cation channels. F1000research. 8 |