Janet Rossant, Ph.D.

Sick Kids 
Stem cell research, Molecular genetics, Developmental biology
"Janet Rossant"

Dr. Janet Rossant is a Senior Scientist in the Developmental & Stem Cell Biology Program and Chief of Research at The Hospital for Sick Children, Toronto. She is also a University Professor, University of Toronto, and Professor in the Departments of Molecular Genetics, Obstetrics/Gynaecology and Paediatrics, University of Toronto. Her research interests centre on understanding the genetic control of normal and abnormal development in the early mouse embryo using both cellular and genetic manipulation techniques. Her interests in the early embryo have led to the discovery of a novel placental stem cell type, the trophoblast stem cell. She is Deputy Scientific Director of the Canadian Stem Cell Network and directs the Centre for Modelling Human Disease in Toronto, which is undertaking genome-wide mutagenesis in mice to develop new mouse models of human disease.

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Mean distance: 17.41 (cluster 57)
Cross-listing: DevTree - Chemistry Tree - GenetiTree

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Huang D, Guo G, Yuan P, et al. (2017) The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during the first developmental cell lineage segregation. Scientific Reports. 7: 17156
Lee CQ, Gardner L, Turco M, et al. (2016) What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast. Stem Cell Reports. 6: 257-272
Frankenberg SR, de Barros FR, Rossant J, et al. (2016) The mammalian blastocyst. Wiley Interdisciplinary Reviews. Developmental Biology
Rossant J. (2016) Making the Mouse Blastocyst: Past, Present, and Future Current Topics in Developmental Biology
Kurmann AA, Serra M, Hawkins F, et al. (2015) Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells. Cell Stem Cell. 17: 527-42
De Los Angeles A, Ferrari F, Xi R, et al. (2015) Hallmarks of pluripotency. Nature. 525: 469-78
Li L, Song L, Liu C, et al. (2015) Ectodermal progenitors derived from epiblast stem cells by inhibition of Nodal signaling. Journal of Molecular Cell Biology
Shojaie S, Ermini L, Ackerley C, et al. (2015) Acellular lung scaffolds direct differentiation of endoderm to functional airway epithelial cells: requirement of matrix-bound HS proteoglycans. Stem Cell Reports. 4: 419-30
Wong AP, Chin S, Xia S, et al. (2015) Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells. Nature Protocols. 10: 363-81
Rossant J. (2015) Mouse and human blastocyst-derived stem cells: vive les differences. Development (Cambridge, England). 142: 9-12
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