Jacqueline A. Lees
Affiliations: | Biology | Massachusetts Institute of Technology, Cambridge, MA, United States |
Area:
tumorigenicityWebsite:
https://ki.mit.edu/people/faculty/leesGoogle:
"Jacqueline A. Lees"Children
Sign in to add trainee| Jeffrey Trimarchi | grad student | (Neurotree) | |
| Ken Moberg | grad student | 1998 | MIT |
| Christopher L. Sansam | post-doc | MIT (Neurotree) |
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Publications
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| Wilson MM, Weinberg RA, Lees JA, et al. (2020) Emerging Mechanisms by which EMT Programs Control Stemness. Trends in Cancer |
| Sharma S, Zhang T, Michowski W, et al. (2020) Targeting the cyclin-dependent kinase 5 in metastatic melanoma. Proceedings of the National Academy of Sciences of the United States of America |
| Dalin S, Sullivan MR, Lau AN, et al. (2019) Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance. Cancer Research |
| Ning JF, Stanciu M, Humphrey MR, et al. (2019) Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma. Nature Communications. 10: 2910 |
| Parisi T, Balsamo M, Gertler F, et al. (2018) The Rb tumor suppressor regulates epithelial cell migration and polarity. Molecular Carcinogenesis |
| Perez DE, Henle AM, Amsterdam A, et al. (2018) Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology. Pigment Cell & Melanoma Research |
| Roper J, Tammela T, Cetinbas NM, et al. (2018) Abstract B38: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis Cancer Research. 78 |
| Guen VJ, Chavarria TE, Kröger C, et al. (2017) EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling. Proceedings of the National Academy of Sciences of the United States of America |
| Guen VJ, Edvardson S, Fraenkel ND, et al. (2017) A homozygous deleterious CDK10 mutation in a patient with agenesis of corpus callosum, retinopathy, and deafness. American Journal of Medical Genetics. Part A |
| Braun CJ, Stanciu M, Boutz PL, et al. (2017) Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma. Cancer Cell |