Amirthaa Suntharalingam
Affiliations: | University of South Florida, Tampa, FL, United States |
Area:
Alzheimer's disease and TauopathiesGoogle:
"Amirthaa Suntharalingam"Mean distance: 106866
Cross-listing: Alzheimer's Tree
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Publications
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Hill SE, Kwon MS, Martin MD, et al. (2019) Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations. The Journal of Biological Chemistry |
Stothert AR, Suntharalingam A, Tang X, et al. (2017) Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma. Scientific Reports. 7: 17951 |
Baker JD, Shelton LB, Zheng D, et al. (2017) Human cyclophilin 40 unravels neurotoxic amyloids. Plos Biology. 15: e2001336 |
Martin MD, Baker JD, Suntharalingam A, et al. (2016) Inhibition of Both Hsp70 Activity and Tau Aggregation In Vitro Best Predicts Tau Lowering Activity of Small Molecules. Acs Chemical Biology |
Stothert AR, Suntharalingam A, Huard DJ, et al. (2014) Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma. Human Molecular Genetics. 23: 6470-80 |
Orwig SD, Chi PV, Du Y, et al. (2014) Ligands for glaucoma-associated myocilin discovered by a generic binding assay. Acs Chemical Biology. 9: 517-25 |
Suntharalingam A, Abisambra JF, O'Leary JC, et al. (2012) Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism. The Journal of Biological Chemistry. 287: 40661-9 |
Abisambra JF, Jinwal UK, Suntharalingam A, et al. (2012) DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau. Journal of Molecular Biology. 421: 653-61 |