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J. Patrick Loria

Affiliations: 
Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
Area:
General Biophysics, Biochemistry
Website:
https://chem.yale.edu/people/j-patrick-loria
Google:
"Patrick Loria"
Bio:

http://xbeams.chem.yale.edu/~loria

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Parents

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Thomas L. Nowak grad student 1997 Notre Dame
 (Active site structure and conformational changes in yeast pyruvate kinase)
Arthur G. Palmer, III post-doc 1997-2001 Columbia

Children

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Gregory Manley grad student Yale
Roger B. Cole grad student 2004 Yale
Dagny L. Ulrich grad student 2005 Yale
Michelle L. Gill grad student 2006 Yale
Thusitha B. Jayasundera grad student 2009 Yale
James M. Lipchock grad student 2010 Yale
yan wang grad student 2010 Yale (Neurotree)
Rebecca B. Berlow grad student 2011 Yale
Eric D. Watt grad student 2012 Yale
Gennady Khirich grad student 2014 Yale
Sean K. Whittier grad student 2014 Yale
Nicolas Doucet post-doc Yale
James G. Kempf post-doc Yale
Evgueni Kovrigin post-doc Yale
George P. Lisi post-doc Yale
Elizabeth M. Moscato-Goodpaster post-doc Yale
Monalisa Swain post-doc Yale

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Publications

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Maschietto F, Morzan UN, Tofoleanu F, et al. (2023) Turning up the heat mimics allosteric signaling in imidazole-glycerol phosphate synthase. Nature Communications. 14: 2239
Shen R, Crean RM, Olsen KJ, et al. (2022) Insights into the importance of WPD-loop sequence for activity and structure in protein tyrosine phosphatases. Chemical Science. 13: 13524-13540
Maschietto F, Zavala E, Allen B, et al. (2022) MptpA Kinetics Enhanced by Allosteric Control of an Active Conformation. Journal of Molecular Biology. 167540
Pinkston J, Jo J, Olsen KJ, et al. (2021) Significant Loop Motions in the SsoPTP Protein Tyrosine Phosphatase Allow for Dual General Acid Functionality. Biochemistry
Medeiros Almeida V, Chaudhuri A, Cangussu Cardoso MV, et al. (2021) Role of a high centrality residue in protein dynamics and thermal stability. Journal of Structural Biology. 213: 107773
Berk JM, Lim C, Ronau JA, et al. (2020) A deubiquitylase with an unusually high-affinity ubiquitin-binding domain from the scrub typhus pathogen Orientia tsutsugamushi. Nature Communications. 11: 2343
Beaumont V, Reiss K, Qu Z, et al. (2020) The allosteric impact of the variable insert loop in Vaccinia H1-related (VHR) phosphatase. Biochemistry
Reiss K, Batista VS, Loria JP. (2020) Allosteric Control of Enzyme Activity: From Ancient Origins to Recent Gene-Editing Technologies. Biochemistry
Jones KM, Zavala E, Loria JP. (2020) Purification and Kinetic Characterization of Protein Tyrosine Phosphatase 1B (1-393) Biophysical Journal. 118: 533a
Cui DS, Lipchock JM, Brookner D, et al. (2019) Uncovering the molecular interactions in the catalytic loop that modulate the conformational dynamics in protein tyrosine phosphatase 1B. Journal of the American Chemical Society
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