Michael P. Cancro, Ph.D.

Affiliations:

1978-

Pathology and Laboratory Medicine

University of Pennsylvania Perelman School of Medicine

Area:

Immunology, B cell development. B cell homeostasis, B cell activation, Immune tolerance, autoimmunity,

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"Michael P. Cancro"

Bio:

Professor Michael P. Cancro obtained his PhD under the tutelage of Dr. Michael Potter at the National Cancer Institute. His doctoral research examined the basis for pristane-induced growth promotion in the murine myeloma model system providing the basis for the widespread use of pristane as a growth promotant in mouse myelomas and hybridomas. His postdoctoral research under Dr. Norman R. Klinman at the University of Pennsylvania was pivotal in developing the influenza hemagglutinin model antigen system, and yielded the first estimate of B cell repertoire diversity to a viral antigen. He subsequently applied this system to understanding developmentally regulated expression of antibody specificities, and was among the first to perform limiting dilution measurements of helper T cell activity.

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